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H<sub>1</sub>-antagonist and mast cell stabilizer
Treatment of ocular itching associated with allergic conjunctivitis.
Adults: 1 drop in each affected eye qd.
Pediatrics: ≥2 Yrs: 1 drop in each affected eye qd.
Sol: 0.2% [2.5mL]
For topical ocular use only; not for inj or oral use. Caution not to touch the eyelids or surrounding areas with the dropper tip to prevent contaminating the dropper tip and solution. Should not be used to treat contact lens-related irritation. Contains benzalkonium chloride, which may be absorbed by soft contact lenses; patients who wear soft contact lenses and whose eyes are not red, should wait at least 10 min after instilling solution before inserting contact lenses. Do not wear contact lens if eye is red.
Cold syndrome, pharyngitis, blurred vision, burning/stinging, conjunctivitis, dry eye, foreign body sensation, hyperemia, hypersensitivity, keratitis, lid edema, pain, asthenia, headache.
Category C, caution in nursing.
H1-antagonist and mast cell stabilizer. Also demonstrates decreased chemotaxis and inhibition of eosinophil activation.
Metabolism: Mono-desmethyl, N-oxide (metabolites). Elimination: (PO) Urine (60-70% unchanged); T1/2=8-12 hrs.
Assess for contact lens use and pregnancy/nursing status.
Monitor for reddening of the eyes and other adverse reactions.
Inform that the drug is for topical ophthalmic administration only. Advise not to touch dropper tip to any surface to prevent contamination. Counsel not to wear contact lens if eyes are red. Advise not to use to treat contact lens-related irritation. Instruct to remove contact lenses prior to instillation of solution; inform that lenses may be reinserted following administration.
2-25°C (36-77°F). Keep bottle tightly closed when not in use.