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  • Pataday
    (olopatadine hydrochloride)

    THERAPEUTIC CLASS

    H<sub>1</sub>-antagonist and mast cell stabilizer

    DEA CLASS

    RX

    INDICATIONS

    Treatment of ocular itching associated with allergic conjunctivitis.

    ADULT DOSAGE

    Adults: 1 drop in each affected eye qd.

    PEDIATRIC DOSAGE

    Pediatrics: ≥2 Yrs: 1 drop in each affected eye qd.

    ADMINISTRATION

    Ocular route.

    HOW SUPPLIED

    Sol: 0.2% [2.5mL]

    WARNINGS/PRECAUTIONS

    For topical ocular use only; not for inj or oral use. Caution not to touch the eyelids or surrounding areas with the dropper tip to prevent contaminating the dropper tip and solution. Should not be used to treat contact lens-related irritation. Contains benzalkonium chloride, which may be absorbed by soft contact lenses; patients who wear soft contact lenses and whose eyes are not red, should wait at least 10 min after instilling solution before inserting contact lenses. Do not wear contact lens if eye is red.

    ADVERSE REACTIONS

    Cold syndrome, pharyngitis, blurred vision, burning/stinging, conjunctivitis, dry eye, foreign body sensation, hyperemia, hypersensitivity, keratitis, lid edema, pain, asthenia, headache.

    PREGNANCY AND LACTATION

    Category C, caution in nursing.

    MECHANISM OF ACTION

    H1-antagonist and mast cell stabilizer. Also demonstrates decreased chemotaxis and inhibition of eosinophil activation.

    PHARMACOKINETICS

    Metabolism: Mono-desmethyl, N-oxide (metabolites). Elimination: (PO) Urine (60-70% unchanged); T1/2=8-12 hrs.

    ASSESSMENT

    Assess for contact lens use and pregnancy/nursing status.

    MONITORING

    Monitor for reddening of the eyes and other adverse reactions.

    PATIENT COUNSELING

    Inform that the drug is for topical ophthalmic administration only. Advise not to touch dropper tip to any surface to prevent contamination. Counsel not to wear contact lens if eyes are red. Advise not to use to treat contact lens-related irritation. Instruct to remove contact lenses prior to instillation of solution; inform that lenses may be reinserted following administration.

    STORAGE

    2-25°C (36-77°F). Keep bottle tightly closed when not in use.