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  • JOINT MOBILITY™ and COLLA FLEX DS


    DIETARY SUPPLEMENT

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    JOINT MOBILITY™ and COLLA FLEX
    DS

    Promotes Healthy Joints1


    1
    THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

    DESCRIPTION

    Joint Mobility and Colla Flex are nutritional supplements for overall joint health.

    Joint Mobility contains undenatured type II collagen, turmeric extract (95% curcumin), boswellia extract and vitamin D3 as active ingredients, and also includes microcrystalline cellulose and silicon dioxide. Joint Mobility is a powder filled capsule that takes on the yellow color of turmeric. Joint Mobility is delivered in a smaller dose than traditional joint supplements. These smaller capsules are ideal for individuals who have trouble taking large capsules or pills.

    Colla Flex contains undenatured type II collagen, turmeric extract, and black pepper extract. Colla Flex is delivered in a smaller dose than traditional joint supplements. These smaller capsules are ideal for individuals who have trouble taking large capsules or pills.1

    BENEFITS AND RESEARCH

    Many people suffer daily from joint pain and discomfort caused from years of overuse or from being obese. Joint pain and a loss of mobility can dramatically affect quality of life, making simple, everyday activity difficult and painful. The ingredients contained in Joint Mobility and Colla Flex work in several different ways to help maintain overall joint health. Turmeric (curcumin) and boswellia extract have been shown to downregulate the genes involved in chronic inflammation. Vitamin D3 has been shown to help increase collagen production which is needed to maintain overall joint health. Black pepper extract has been shown to block the expression of inflammatory markers in the body. The ingredients contained in these supplements have been shown to inhibit pro-inflammatory pathways and also help to prevent the breakdown of joint collagen, allowing the body to repair and heal itself.1

    SUGGESTED USAGE

    Joint Mobility: Take two capsules daily.

    Colla Flex: Take one capsule daily.

    SAFETY AND WARNINGS

    Joint Mobility and Colla Flex are generally well tolerated. As with any dietary supplement, some gastrointestinal discomfort may be experienced.

    HOW SUPPLIED

    Available in capsules.

    REFERENCES

    Crowley DC, Lau FC, Sharma P, et al. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci 2009, 6:312-321.

    Chandran B, Goel A. A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis. Phytother Res. 2012 Nov; 26(11):1719-25.

    Dobak J1, Grzybowski J, et al. 1,25-Dihydroxyvitamin D3 increases collagen production in dermal fibroblasts. J Dermatol Sci. 1994 Aug;8(1):18-24.

    Kimmatkar N, Thawani V, et al. Efficacy and tolerability of Boswellia serrate extract in treatment of osteoarthritis of knee—a randomized double bling placebo controlled trial. Phytomedicine 2003 Jan; 10(1):3-7.

    Reuter S, Gupta S, et al. Epigenetic changes induced by curcumin and other natural compounds. Genes Nutr (2011) 6:93–108.

    Takada Y, Ichikawa H, et al. Acetyl-11-Keto-β-Boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-κΒ and NF- κΒ- regulated gene expression. J Immunol 2006;176:3127-3140.

    Ying X, Chen X, Cheng S, Shen Y, Peng L, Xu HZ. Piperine inhibits IL-β induced expression of inflammatory mediators in human osteoarthritis chondrocyte. Int Imunopharmacol. 2013;17(2):293-299.

    PRODUCT PHOTO

    NOTE: These photos can be used only for identification by shape, color, and imprint. They do not depict actual or relative size.

    The product samples shown here have been supplied by the manufacturer and reproduced in full color by PDR as a quick-reference identification aid. While every effort has been made to assure accurate reproduction, please remember that any visual identification should be considered preliminary. In cases of poisoning or suspected over dosage, the drug's identity should be verified by chemical analysis.

    Image from Drug Label Content