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Accolate is a medicine used for the prevention of asthma attacks and for long-term treatment of asthma.
How does this medication work?
Accolate works by blocking the action of substances in the body that cause symptoms of asthma.
This medicine is not used for immediate treatment of a sudden asthma attack. Always follow the instructions your healthcare provider gave you for treating an asthma attack.
What are the beneficial effects of this medication and when should I begin to have results?
What: Accolate has been shown to improve morning and daytime asthma symptoms, and decrease nighttime awakenings due to asthma symptoms. Accolate may also reduce the need for a rescue inhaler.
When: Accolate may start improving your asthma symptoms within one week.
How do I know it is working?
You may feel an improvement in your breathing once you begin using Accolate. This is a good indicator that your medication is working. Your healthcare provider may perform tests to check your lung function and ask you questions to assess how well your symptoms are controlled.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Adults and Children ≥12 Years
More common side effects may include: headache, infection, nausea, diarrhea, pain.
Children 5-11 Years
More common side effects may include: headache, stomach pain.
Less common side effects of Accolate may include:
Severe liver problems, with symptoms such as pain or tenderness in the right upper side of your abdomen (stomach area), nausea, tiredness, itchiness, yellowing of your skin or the whites of your eyes, flu-like symptoms, loss of appetite, or dark (tea-colored) urine.
Inflammation of your blood vessels, with symptoms such as a feeling of pins and needles or numbness of your arms and legs, flu-like symptoms, rash, or pain and swelling in your sinuses.
Changes in behavior or mood, trouble sleeping, or depression.
Do not take Accolate if you are allergic to it or any of its ingredients.
Do not take Accolate if you have liver problems.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Accolate. Also, talk to your healthcare provider about your complete medical history, especially if you have liver problems, or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults and children ≥12 years: The recommended dose is 20 milligrams (mg) twice a day.
Children 5-11 years: The recommended dose is 10 mg twice a day.
Take Accolate exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Accolate without first talking with your healthcare provider.
Take Accolate at least 1 hour before or 2 hours after meals.
Do not take Accolate if you need relief right away for a sudden asthma attack.
If Accolate is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Accolate with the following: aspirin, blood pressure/heart medications known as calcium channel blockers (such as amlodipine or nifedipine), carbamazepine, cisapride, cyclosporine, erythromycin, phenytoin, theophylline, tolbutamide, or warfarin.
The effects of Accolate during pregnancy are unknown. Accolate can be found in your breast milk if you take it while breastfeeding. Do not take Accolate while you are breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of Accolate, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature. Protect from light and moisture.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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