PDR MEMBER LOGIN:
  • Required field
  • Generic Name: (zafirlukast)
    Other Brands: N/A
  • Last Revised: 01/2015
    • What is this medication and its most common uses?

      Accolate is a medicine used for the prevention of asthma attacks and for long-term treatment of asthma.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Accolate works by blocking the action of substances in the body that cause symptoms of asthma.

      This medicine is not used for immediate treatment of a sudden asthma attack. Always follow the instructions your healthcare provider gave you for treating an asthma attack.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Accolate has been shown to improve morning and daytime asthma symptoms, and decrease nighttime awakenings due to asthma symptoms. Accolate may also reduce the need for a rescue inhaler.

      When: Accolate may start improving your asthma symptoms within one week.

      How do I know it is working?

      You may feel an improvement in your breathing once you begin using Accolate. This is a good indicator that your medication is working. Your healthcare provider may perform tests to check your lung function and ask you questions to assess how well your symptoms are controlled.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Adults and Children ≥12 Years

      More common side effects may include: headache, infection, nausea, diarrhea, pain.

      Children 5-11 Years

      More common side effects may include: headache, stomach pain.

      Less common side effects of Accolate may include:

      Severe liver problems, with symptoms such as pain or tenderness in the right upper side of your abdomen (stomach area), nausea, tiredness, itchiness, yellowing of your skin or the whites of your eyes, flu-like symptoms, loss of appetite, or dark (tea-colored) urine.

      Inflammation of your blood vessels, with symptoms such as a feeling of pins and needles or numbness of your arms and legs, flu-like symptoms, rash, or pain and swelling in your sinuses.

      Changes in behavior or mood, trouble sleeping, or depression.

    • Who should not take this medication?

      Do not take Accolate if you are allergic to it or any of its ingredients.

      Do not take Accolate if you have liver problems.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Accolate. Also, talk to your healthcare provider about your complete medical history, especially if you have liver problems, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults and children ≥12 years: The recommended dose is 20 milligrams (mg) twice a day.

      Children 5-11 years: The recommended dose is 10 mg twice a day.

    • How should I take this medication?

      Take Accolate exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Accolate without first talking with your healthcare provider.

      Take Accolate at least 1 hour before or 2 hours after meals.

    • What should I avoid while taking this medication?

      Do not take Accolate if you need relief right away for a sudden asthma attack.

    • What are the possible food and drug interactions associated with this medication?

      If Accolate is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Accolate with the following: aspirin, blood pressure/heart medications known as calcium channel blockers (such as amlodipine or nifedipine), carbamazepine, cisapride, cyclosporine, erythromycin, phenytoin, theophylline, tolbutamide, or warfarin.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Accolate during pregnancy are unknown. Accolate can be found in your breast milk if you take it while breastfeeding. Do not take Accolate while you are breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Accolate, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature. Protect from light and moisture.

    • Who should I contact in case of emergency or overdose?
      back to top

      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
  •  
  • Terms of Service

    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.