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  • Generic Name: (ursodiol)
    Other Brands: N/A
  • Last Revised: 05/2014
    • What is this medication and its most common uses?

      Actigall is a medicine used to dissolve gallstones in people who do not want surgery or cannot have surgery. Actigall is also used to prevent the formation of gallstones in people losing weight quickly.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Actigall is a bile acid (a substance naturally produced by the body that is stored in the gallbladder) and works by dissolving cholesterol in bile so that it cannot form stones.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: In studies, Actigall has been shown to completely dissolve gallstones in 81% of patients.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. Gallstone treatment with Actigall may require months of therapy. It is important that you take Actigall exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may perform ultrasounds at 6-month intervals during the first year of therapy to monitor gallstone response.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Common side effects may include: infection, abdominal (stomach area) pain, diarrhea, heartburn, nausea, headache, sinus pain and congestion.

    • Who should not take this medication?

      Do not take Actigall if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Actigall. Also, talk to your healthcare provider about your complete medical history, especially if you have liver problems.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Gallstone Treatment

      Adults: Your healthcare provider will prescribe the appropriate dose for you, based on your weight.

      Gallstone Prevention

      Adults: The recommended dose is 300 milligrams twice a day.

    • How should I take this medication?

      Take Actigall exactly as prescribed by your healthcare provider.

    • What should I avoid while taking this medication?

      Do not change your dose or stop taking Actigall without first talking to your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      If Actigall is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Actigall with the following: antacids containing aluminum, bile acid binders (such as cholestyramine or colestipol), birth control pills, clofibrate, or estrogens.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Actigall during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Actigall, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.