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  • Generic Name: (loxapine)
    Other Brands: N/A
  • Last Revised: 10/2014
    • What is this medication and its most common uses?

      Adasuve is a medicine used to treat agitation in adults with schizophrenia or bipolar I disorder. Adasuve is available as an inhaler.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Adasuve is thought to work by changing the level of excitability in the brain, thereby reducing the symptoms of agitation.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Adasuve has been shown to reduce tension, hostility, uncooperativeness, and excitement, as well as improve impulse control.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider’s directions. It is important that you receive Adasuve exactly as your healthcare provider has prescribed.

      How do I know it is working?

      You may notice an improvement in your symptoms of agitation once you start receiving Adasuve. Your healthcare provider may ask you questions from time to time to assess how well your symptoms are controlled.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Adasuve may cause narrowing of the airways that can cause you to have problems breathing or to stop breathing. People who have asthma or other airway or lung problems (such as chronic obstructive pulmonary disease [COPD]) have a higher risk of this. Tell your healthcare provider right away if you experience any symptoms of airway narrowing, such as wheezing, coughing, chest tightness, and shortness of breath.

      Adasuve may also increase the risk of death in elderly people with psychosis due to dementia (confusion and memory loss). Adasuve is not approved for the treatment of patients with dementia-related psychosis.

      More common side effects may include: changes in taste, drowsiness, sore throat.

      Less common side effects may include:

      Neuroleptic malignant syndrome (NMS) (a life-threatening brain disorder), with symptoms such as high fever, excessive sweating, muscle rigidity, confusion, changes in your breathing, fast or irregular heartbeat, or changes in your blood pressure.

      Adasuve may also cause low blood pressure, seziures, worsening of glaucoma, or difficulty urinating.

    • Who should not take this medication?

      Your healthcare provider will not administer Adasuve to you if you are allergic to it or any of its ingredients.

      Your healthcare provider will not administer Adasuve to you if you have or have had asthma, COPD, or other lung problems that can cause airway narrowing, or if you are taking medicines to treat asthma or COPD.

      Your healthcare provider will not administer Adasuve to you if you are experiencing wheezing, coughing, chest tightness, or shortness of breath.

      Your healthcare provider will not administer Adasuve to you if you have taken it before and experience airway narrowing.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Adasuve. Also, talk to your healthcare provider about your complete medical history, especially if you have high or low blood pressure, heart problems or a history of stroke, seizures, drink alcohol or abuse medicine, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Your healthcare provider will prescribe the appropriate dose for you.

    • How should I take this medication?

      Your healthcare provider will administer Adasuve to you.

    • What should I avoid while taking this medication?

      Do not drink alcohol while you are receiving Adasuve.

      Do not drive, operate heavy machinery, or engage in other dangerous activities until you know how Adasuve affects you.

    • What are the possible food and drug interactions associated with this medication?

      If Adasuve is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Adasuve with the following: alcohol, atropine, ipratroprium, or medications that slow down your brain function (such as amitriptyline, hydrocodone, or lorazepam).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Adasuve during pregnancy and breastfeeding are unknown. Do not breastfeed while you are receiving Adasuve. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss your scheduled dose, contact your healthcare provider or pharmacist for advice.

    • How should I store this medication?

      Your healthcare provider will store this mediction for you.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.