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Azulfidine is a medicine used to prolong remission (a period during which the symptoms of a disease stop) of ulcerative colitis (an inflammatory disease of the large intestine) and to treat mild to moderate ulcerative colitis. Azulfidine is also used with certain other medications to treat severe ulcerative colitis.
How does this medication work?
Azulfidine is thought to work by blocking a substance in your body that is involved in causing inflammation and pain in the colon.
What are the beneficial effects of this medication and when should I begin to have results?
What: Azulfidine may help to treat and keep your ulcerative colitis in remission.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Azulfidine exactly as your healthcare provider has prescribed.
How do I know it is working?
You may experience fewer symptoms, such as no rectal bleeding and less frequent bowel movements once you start treatment with Azulfidine.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: loss of appetite, headache, nausea, vomiting, indigestion, temporary reduced sperm count.
Less common side effects may include:
Azulfidine can cause serious allergic reactions that may affect your organs and other parts of your body, such as your liver and blood cells. Symptoms may include, skin rash, hives, skin blisters or peeling of your skin, sores in your mouth; trouble swallowing or breathing; swelling of your face, eyes, lips, or tongue; fever, shortness of breath, swelling of the legs; or dark-colored urine, yellowing of your skin or the whites of your eyes.
Azulfidine may also cause an orange-yellow discoloration of the urine or skin.
Do not take Azulfidine if you are allergic to it, any of its ingredients, or to aspirin or medicines that contain aspirin.
Do not take Azulfidine if you have porphyria (a blood disorder).
Do not take Azulfidine if you have a blockage in your intestines or urinary tract.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Azulfidine. Also, talk to your healthcare provider about your complete medical history, especially if you have asthma; blood, liver, or kidney problems; an infection; glucose-6-phosphate dehydrogenase deficiency (lack of an enzyme responsible for the breakdown of red blood cells); or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: Your healthcare provider will prescribe the appropriate dose for you, based on your response and tolerance to treatment.
Children ≥6 years: Your healthcare provider will prescribe the appropriate dose for your child, based on his/her body weight.
Take Azulfidine exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Azulfidine without first talking to your healthcare provider.
Take Azulfidine in evenly divided doses, preferably after meals.
Do not become dehydrated while taking Azulfidine. Drink plenty of fluids while you are taking Azulfidine.
If Azulfidine is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Azulfidine with the following: digoxin or folic acid.
The effects of Azulfidine during pregnancy are unknown. Azulfidine can be found in your breast milk if you take it while breastfeeding. If you breastfeed while taking Azulfidine, check your baby for diarrhea or bloody stools. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of Azulfidine, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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