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Baraclude is a medicine used to treat chronic (long-term) hepatitis B infection when the disease is progressing and there is liver inflammation. Baraclude is available as tablets and an oral solution.
How does this medication work?
Baraclude works by lowering the ability of the virus to multiply in your body, thereby helping to stop the virus from spreading.
Baraclude does not cure hepatitis B. See your healthcare provider regularly.
What are the beneficial effects of this medication and when should I begin to have results?
What: Baraclude may lower the amount of hepatitis B virus in your body, improving the condition of your liver.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Baraclude exactly as your healthcare provider has prescribed.
How do I know it is working?
Your healthcare provider may order tests regularly to check how well this medication is working.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
If you stop taking Baraclude, you may get a "flare-up" of your hepatitis. A "flare-up" is when the disease suddenly returns in a worse way than before. If you stop taking Baraclude, your healthcare provider may monitor you closely for several months to check for hepatitis that could be getting worse.
If you have or get HIV that is not being treated with medicines while taking Baraclude, the HIV virus may develop resistance to certain HIV medicines and become harder to treat. Your healthcare provider may test you for HIV-1 infection before and during treatment with Baraclude.
Baraclude can cause a serious condition called lactic acidosis (a build-up of an acid in the blood). This serious medical emergency must be treated in the hospital. Call your healthcare provider right away if you feel very weak, tired, dizzy, or lightheaded; have unusual muscle pain or stomach pain with nausea and vomiting; trouble breathing; you feel cold, especially in your arms and legs; or have a fast or irregular heartbeat.
Baraclude can also cause serious liver problems (an enlarged or fatty liver) that can lead to death. Call your healthcare provider right away if you develop yellowing of your skin or the whites of your eyes, dark-colored urine or light-colored stools, loss of appetite for several days or longer, have nausea or lower abdominal (stomach area) pain.
Common side effects may include: headache, tiredness, dizziness, nausea.
Do not take Baraclude if you are allergic to it or any of its ingredients.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Baraclude. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney problems, received medicine for hepatitis B infection before, have hepatitis B virus in your blood regularly, or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults and adolescents ≥16 years: The recommended dose is 0.5 to 1 milligram once a day.
Children ≥2 years and weighing ≥10 kilograms: Your healthcare provider will prescribe the appropriate dose for your child, based on his/her weight.
If you have kidney impairment, your healthcare provider may adjust your dose appropriately.
Take Baraclude exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Baraclude without first talking to your healthcare provider.
Take Baraclude on an empty stomach (at least 2 hours after a meal and 2 hours before the next meal).
If you are taking Baraclude oral solution, hold the dosing spoon in a vertical position and fill it gradually to the mark corresponding to the prescribed dose. Rinse the dosing spoon with water after taking each dose.
Do not run out of Baraclude. When your supply of Baraclude starts to run low, call your healthcare provider or pharmacy.
Do not share personal items that can have blood or body fluids on them (such as toothbrushes or razor blades).
If Baraclude is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Baraclude with any medicines that affect your kidneys.
The effects of Baraclude during pregnancy and breastfeeding are unknown. Do not breastfeed while you are taking Baraclude. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you become pregnant while taking Baraclude, talk to your healthcare provider about registering with the Antiretroviral Pregnancy Registry. The purpose of this registry is to collect information about the safety of this medicine during pregnancy.
If you miss a dose of Baraclude, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature. Protect from light.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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