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Dapsone is a medicine used to treat dermatitis herpetiformis (a chronic, very itchy skin rash made up of bumps and blisters) and leprosy (a chronic, curable infection mainly causing skin lesions and nerve damage).
How does this medication work?
Dapsone works by stopping the growth of bacteria.
What are the beneficial effects of this medication and when should I begin to have results?
What: Dapsone may help treat your skin condition.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. It is important that you take dapsone exactly as your healthcare provider has prescribed.
How do I know it is working?
Your healthcare provider may perform tests and ask you questions to assess how well your condition is being treated.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: rupture or destruction of red blood cells.
Less common side effects may include:
Blood problems, including decreased blood cell counts, with symptoms such as a sore throat, fever, paleness, a rash of purple spots on the skin, or yellowing of the skin or whites of the eyes. Your healthcare provider should check your blood cell counts during treatment with dapsone.
Serious allergic reactions with symptoms such as skin rash, bulls-eye-shaped lesions on the skin, hives, or tender bumps under the skin.
Dapsone may also cause liver problems.
Do not take dapsone if you are allergic to it or any of its ingredients.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with dapsone. Also, talk to your healthcare provider about your complete medical history, especially if you have liver problems, glucose-6-phosphate dehydrogenase (G6PD) deficiency (lack of an enzyme responsible for the breakdown of red blood cells), or certain blood disorders, or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The recommended starting dose is 50 milligrams (mg) daily. Your healthcare provider may adjust your dose as needed.
Children: Your healthcare provider will prescribe the appropriate dose for your child.
Adults: The recommended dose is 100 mg daily.
Take dapsone exactly as prescribed by your healthcare provider.
Do not change your dose or stop taking dapsone without first talking to your healthcare provider.
If dapsone is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining dapsone with the following: pyrimethamine, rifampin, or trimethoprim.
The effects of dapsone during pregnancy are unknown. Dapsone can pass into your breast milk. Do not breastfeed while you are taking dapsone. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of dapsone, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature. Protect from light.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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