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  • Generic Name: (daunorubicin hydrochloride)
    Other Brands: N/A
  • Last Revised: 05/2014
    • What is this medication and its most common uses?

      Daunorubicin is an anticancer medicine used with other medicines to treat leukemia (a type of cancer of the white blood cells). Daunorubicin is administered as intravenous (directly into a vein) injections.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Daunorubicin is thought to work by slowing or stopping the growth of cancer cells in the body.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: By stopping the growth of cancer cells, daunorubicin may help to relieve your symptoms associated with cancer.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions.

      How do I know it is working?

      Your healthcare provider may order tests regularly to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Daunorubicin is administered in a hospital or medical facility under the supervision of your healthcare provider who is experienced in administering chemotherapy medicines.

      Daunorubicin is administered as intravenous injections. If the medicine accidently leaks out into the space or tissue around the infusion site, destruction of skin tissue cells may occur.

      Daunorubicin may cause heart problems, including life-threatening congestive heart failure (a condition in which the heart cannot pump enough blood throughout the body), which may occur during treatment or months to years after you stop receiving treatment.

      Daunorubicin may cause a severe decrease in the number of blood cells in your bone marrow, with symptoms such as infection or bleeding.

      Tell your healthcare provider if you have kidney or liver impairment. Your healthcare provider may adjust your dose appropriately.

      More common side effects may include: hair loss, nausea, vomiting, diarrhea, abdominal (stomach area) pain.

      Less common side effects may include:

      Harm to your unborn baby. Tell your healthcare provider right away if you become pregnant while receiving daunorubicin.

      Daunorubicin may cause a temporary red coloration to your urine.

    • Who should not take this medication?

      Your healthcare provider will not administer daunorubicin to you if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with daunorubicin. Also, talk to your healthcare provider about your complete medical history, especially if you have liver, kidney, or heart problems; any infections; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults and children: Your healthcare provider will prescribe the appropriate dose for you, based on your weight.

      If you have kidney or liver impairment, your healthcare provider may adjust your dose appropriately.

    • How should I take this medication?

      Your healthcare provider will administer daunorubicin to you.

    • What should I avoid while taking this medication?

      Do not miss any scheduled follow-up appointments with your healthcare provider.

      Do not become pregnant or breastfeed while you are receiving daunorubicin.

    • What are the possible food and drug interactions associated with this medication?

      If daunorubicin is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining daunorubicin with the following: medicines that harm your liver (such as methotrexate) or other cancer medicines (such as cyclophosphamide).

    • May I receive this medication if I am pregnant or breastfeeding?

      Daunorubicin may harm your unborn baby if you receive it during pregnancy. Do not become pregnant or breastfeed while you are receiving daunorubicin. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      Daunorubicin should be given under special circumstances determined by your healthcare provider. If you miss your scheduled dose, contact your healthcare provider or pharmacist for advice.

    • How should I store this medication?

      Your healthcare provider will store this medication for you.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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