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DDAVP nasal spray is a medicine used to manage a type of diabetes called diabetes insipidus. DDAVP nasal spray is also used to manage excessive thirst and production of urine following a head trauma or surgery.
How does this medication work?
DDAVP nasal spray works by replacing vasopressin (a hormone that is normally produced in the body to help balance the amount of water and sodium [salt]), thereby improving your symptoms.
What are the beneficial effects of this medication and when should I begin to have results?
What: DDAVP nasal spray has been shown to decrease urinary frequency.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you use DDAVP nasal spray exactly as your healthcare provider has prescribed.
How do I know it is working?
You may feel an improvement in your symptoms after you start using DDAVP nasal spray. Your healthcare provider may ask you a series of questions from time to time that will help assess how well your symptoms are controlled with treatment.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: headache, runny nose.
Less common side effects may include:
Low blood sodium levels, with symptoms such as headache, nausea, vomiting, weight gain, restlessness, tiredness, disorientation, depressed reflexes, loss of appetite, irritability, muscle weakness, muscle spasms or cramps, or abnormal mental status (including hallucinations).
Do not use DDAVP nasal spray if you are allergic to it or any of its ingredients.
Do not use DDAVP nasal spray if you have kidney problems.
Do not use DDAVP nasal spray if you have or have had low blood sodium levels in your body.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with DDAVP nasal spray. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or heart problems; high blood pressure; cystic fibrosis; scarring, swelling, or any other disease in your nose; or if you drink excessive amounts of water.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The usual dose is 0.1 to 0.4 milliliters (mL) a day, either as a single dose or divided into two or three doses, as directed by your healthcare provider.
Children 3 months-12 years: The usual dose is 0.05 to 0.3 mL a day, either as a single dose or divided into two doses, as directed by your healthcare provider.
Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.
Use DDAVP nasal spray exactly as prescribed by your healthcare provider. Do not use it more often or stop using DDAVP nasal spray without first talking to your healthcare provider.
Prime DDAVP nasal spray before using it by pressing down four times.
Please review the instructions that came with your prescription on how to properly use DDAVP nasal spray.
Always follow your healthcare provider's instructions regarding fluid intake while using DDAVP nasal spray.
Do not drink excessive amounts of water or other fluids while you are using DDAVP nasal spray.
Do not transfer any remaining solution to another bottle. Throw away any remaining medicine after 50 doses.
If DDAVP nasal spray is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining DDAVP nasal spray with the following: carbamazepine, certain antidepressants (such as amitriptyline or sertraline), chlorpromazine, lamotrigine, narcotic painkillers (such as oxycodone or hydrocodone), or nonsteroidal anti-inflammatory drugs (NSAIDS) (such as ibuprofen or naproxen).
The effects of DDAVP nasal spray during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of DDAVP nasal spray, use it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not use two doses at once.
Store at room temperature, in an upright position.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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