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  • Generic Name: (desmopressin acetate)
    Other Brands: N/A
  • Last Revised: 05/2014
    • What is this medication and its most common uses?

      DDAVP tablets contain a medicine used to manage a type of diabetes called diabetes insipidus. DDAVP tablets are also used to manage excessive thirst and production of urine following a head trauma or surgery. DDAVP tablets are also used to manage nighttime bedwetting.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      DDAVP tablets work by replacing vasopressin (a hormone that is normally produced in the body to help balance the amount of water and sodium [salt]), thereby improving your symptoms.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: DDAVP tablets have been shown to reduce the incidence of bedwetting.

      When: DDAVP tablets may start working within 1 hour of taking them.

      How do I know it is working?

      You may feel an improvement in your symptoms after you start taking DDAVP tablets. Your healthcare provider may ask you a series of questions from time to time that will help assess how well your symptoms are controlled with treatment.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: headache.

      Less common side effects may include:

      Low blood sodium levels, with symptoms such as headache, nausea, vomiting, weight gain, restlessness, tiredness, disorientation, depressed reflexes, loss of appetite, irritability, muscle weakness, muscle spasms or cramps, or abnormal mental status (including hallucinations).

    • Who should not take this medication?

      Do not take DDAVP tablets if you are allergic to them or any of their ingredients.

      Do not take DDAVP tablets if you have kidney problems.

      Do not take DDAVP tablets if you have or have had low blood sodium levels in your body.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with DDAVP tablets. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or heart problems, high blood pressure, cystic fibrosis, or if you drink excessive amounts of water.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Diabetes Insipidus

      Adults and children ≥4 years: The recommended starting dose is 0.05 milligrams (mg) twice a day.

      Nighttime Bedwetting

      Adults and children ≥6 years: The recommended starting dose is 0.2 mg at bedtime.

      Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

    • How should I take this medication?

      Take DDAVP tablets exactly as prescribed by your healthcare provider. Do not change your dose or stop taking DDAVP tablets without first talking to your healthcare provider.

      Always follow your healthcare provider's instructions regarding fluid intake while taking DDAVP tablets.

    • What should I avoid while taking this medication?

      Do not drink excessive amounts of water or other fluids while you are taking DDAVP tablets.

    • What are the possible food and drug interactions associated with this medication?

      If DDAVP tablets are taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining DDAVP tablets with the following: carbamazepine, certain antidepressants (such as amitriptyline or sertraline), chlorpromazine, lamotrigine, narcotic painkillers (such as oxycodone or hydrocodone), or nonsteroidal anti-inflammatory drugs (NSAIDS) (such as ibuprofen or naproxen).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of DDAVP tablets during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of DDAVP tablets, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature. Protect from excessive heat or light.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
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