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Egrifta is a medicine used to reduce excessive abdominal (stomach area) fat in people with HIV-infection. Egrifta is administered subcutaneously (just below the skin).
How does this medication work?
Egrifta is thought to work with your own body to produce natural growth hormone to reduce your excess fat.
What are the beneficial effects of this medication and when should I begin to have results?
What: In clinical trials, Egrifta has been shown to reduce abdominal fat tissue by an average of 14-18%.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you use Egrifta exactly as your healthcare provider has prescribed.
How do I know it is working?
You may notice an improvement in the appearance of your abdominal area. This is a good indication that Egrifta is working.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: joint pain, injection-site redness or itching, pain or swelling in your arms or legs, muscle pain.
Less common side effects may include:
Serious allergic reactions with symptoms such as a rash, hives, swelling of your face or throat, shortness of breath or trouble breathing, fast heartbeat, or feeling of faintness or fainting.
Egrifta may also increase your blood sugar levels.
Do not use Egrifta if you are allergic to it or any of its ingredients.
Do not use Egrifta if you have cancer (either newly diagnosed or recurrent) or are receiving treatment for cancer.
Do not use Egrifta if you have a pituitary gland tumor, pituitary gland surgery, or other problems related to your pituitary gland.
Do not use Egrifta if you are pregnant.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Egrifta. Also, talk to your healthcare provider about your complete medical history, especially if you have diabetes, kidney or liver problems, have or have had cancer, or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The recommended dose is 2 milligrams once a day.
Use Egrifta exactly as prescribed by your healthcare provider. Do not use extra doses or stop using it without first talking to your healthcare provider.
Your healthcare provider will give you instructions on how to prepare and inject Egrifta.
Inject Egrifta under the skin of your stomach area. Do not inject Egrifta into scar tissue, bruises, or your navel (belly button). Every time you inject Egrifta, rotate the injection site.
Once you mix Egrifta, use it right away and throw away any unused medicine. Do not store mixed Egrifta.
Please review the instructions that came with your prescription on how to properly inject Egrifta.
Do not use Egrifta until your healthcare provider shows you how to use it correctly.
Do not use Egrifta if the solution is cloudy, discolored, or has particles in it after mixing.
Do not miss any scheduled follow-up appointments with your healthcare provider.
Do not share needles or syringes with other people. Sharing of needles can result in the spread of HIV infection to others.
If Egrifta is used with certain other drugs, the effects of either could be increased, decreased, or altered. Egrifta may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.
Do not become pregnant while you are using Egrifta. The effects of Egrifta during breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
The Centers for Disease Control and Prevention recommend that HIV- infected mothers not breastfeed their infants to avoid risking transmission of the virus to the child.
If you miss a dose of Egrifta, use it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not use two doses at once.
Store Egrifta in the refrigerator. Protect from light.
Store sterile water for injection, syringes, and needles at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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