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  • Generic Name: (panobinostat)
    Other Brands: N/A
  • Last Revised: 06/2016
    • What is this medication and its most common uses?

      Farydak is a medicine used in combination with other medicines to treat a type of cancer called multiple myeloma in people who have tried other medicines.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Farydak is thought to work by stopping or slowing the growth of cancer cells.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Farydak used in combination with certain other medicines has been shown to slow the progression of multiple myeloma.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. It is important that you take Farydak exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may order certain tests to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Farydak may cause severe diarrhea. Notify your healthcare provider if you experience abdominal (stomach) cramps, loose stools, or diarrhea, or if you feel like you are becoming dehydrated.

      Farydak may also cause severe, life-threatening heart problems, including severe heart rhythm problems. Your healthcare provider may order certain tests to monitor your heart before and during treatment with Farydak. Notify your healthcare provider right away if you experience chest pain, faster or slower heart beat, palpitations (feel like your heart is racing), feeling lightheaded or faint, dizziness, blue-colored lips, shortness of breath, or swelling in your legs.

      More common side effects may include: diarrhea, tiredness, nausea, swelling in your arms or legs, decreased appetite, fever, vomiting.

      Less common side effects may include:

      Severe bleeding, with symptoms such as blood in your stools or black stools, pink or brown urine, unexpected bleeding or bleeding that is severe or that you cannot control, vomiting or coughing up blood, increased bruising, feeling dizzy or weak, confusion, changes in your speech, or a headache that lasts a long time.

      Low blood cell counts, with symptoms such as unusual bleeding or bruising under your skin, infections, feeling weak or tired, paleness, or shortness of breath.

      Increased risk of infections, with symptoms such as fever, sweats or chills, cough, or flu-like symptoms.

      Liver problems, with symptoms such as feeling tired or weak, loss of appetite, dark-colored urine, upper abdominal (stomach) pain, or yellowing of your skin or the whites of your eyes.

      Harm to your unborn baby. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • Who should not take this medication?

      Do not take Farydak if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Farydak. Also, talk to your healthcare provider about your complete medical history, especially if you have diarrhea, heart problems, a history of bleeding problems, an infection, or liver problems, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended starting dose is 20 milligrams once every other day (3 doses per week) in weeks 1 and 2 of a 21-day cycle.

      Your healthcare provider may adjust your dose as needed.

      If you have liver impairment or take certain other medicines, your healthcare provider may adjust your dose appropriately.

    • How should I take this medication?

      Take Farydak exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Farydak without first talking to your healthcare provider.

      Take Farydak at about the same time each scheduled day, either with or without food.

      Swallow Farydak whole with a cup of water. Do not open, crush, or chew the capsules.

      It is important that females use effective birth control while taking Farydak and for at least 3 months after the last dose of Farydak. It is important that men use condoms while on treatment and for 6 months after their last dose.

    • What should I avoid while taking this medication?

      Do not allow direct contact of the powder in the Farydak capsules with your skin or eyes. If you accidentally get powder on your skin, wash the area with soap and water. If you accidentally get powder in your eyes, flush your eyes with water.

      Do not eat grapefruit, star fruit, or pomegranate, nor drink grapefruit juice or pomegranate juice while taking Farydak.

    • What are the possible food and drug interactions associated with this medication?

      If Farydak is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Farydak may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      Farydak can harm your unborn baby if you take it during pregnancy. Do not become pregnant or breastfeed while you are taking Farydak. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Farydak, take it as soon as possible (up to 12 hours after the time the dose should have been taken). If you vomit after taking Farydak, do not take another dose, and return to your regular dosing schedule.

    • How should I store this medication?

      Store at room temperature. Protect from light.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.