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Gamunex-C is a medicine used to treat a condition called primary immune deficiency. Gamunex-C is given subcutaneously (injected directly under your skin) for the treatment of primary immune deficiency. Gamunex-C may also be used to treat other conditions, as determined by your healthcare provider.
How does this medication work?
People with primary immune deficiency lack the healthy antibodies needed to fight off infections. Gamunex-C provides those healthy antibodies.
What are the beneficial effects of this medication and when should I begin to have results?
What: In a clinical study, Gamunex-C prevented sinus infections and pneumonia in the people who received it.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Gamunex-C exactly as your healthcare provider has prescribed.
How do I know it is working?
You may notice a decrease in the number and severity of your infections after you start using Gamunex-C.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
A blood clot may develop in your body while you are using Gamunex-C. Contact your healthcare provider immediately if you experience signs or symptoms of a blood clot, such as pain and/or swelling of an arm or leg with warmth over the affected area, discoloration of an arm or leg, unexplained shortness of breath, chest pain or discomfort that worsens on deep breathing, unexplained fast heartbeat, or numbness or weakness on one side of the body.
Kidney problem, including kidney failure, may occur while you are using Gamunex-C. Contact your healthcare provider right away if you develop any symptoms, such as decreased urination, sudden weight gain, fluid retention, swelling in your legs, or shortness of breath.
More common side effects may include: redness, swelling, and itching at the injection site; headache; tiredness; joint pain; fever.
Less common side effects may include:
Severe allergic reaction, with symptoms such as hives, trouble breathing, wheezing, dizziness, or fainting.
A type of brain inflammation called aseptic meningitis, with symptoms such as severe headache, stiff neck, tiredness, fever, sensitivity to light, painful eye movements, nausea, or vomiting.
A type of blood problem called hemolytic anemia, with symptoms such as increased heart rate, tiredness, yellowing of your skin or the whites of your eyes, or dark colored urine.
A lung problem called transfusion-related acute lung injury, with symptoms such as chest pain; trouble breathing; blue lips, arms, or legs; or fever.
Do not use Gamunex-C if you are allergic to it or any of its ingredients.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Gamunex-C. Also, talk to your healthcare provider about your complete medical history, especially if you have heart or kidney problems, a blood clotting disorder, diabetes, or history of a blood clot in a vein or artery.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults and children ≥2 years: Your healthcare provider will prescribe the appropriate dose for you based on your previous medication.
Use Gamunex-C exactly as prescribed by your healthcare provider. Only use Gamunex-C by yourself after you have been trained by your healthcare provider.
One or more injection sites on your body will be selected. The number and location of the injection sites depends on the amount of Gamunex-C you need to receive. Typically, people use 4 infusion sites on their body. You may use up to 8 infusion sites as directed by your healthcare provider.
The needles are attached with a tube to the pump.
You will need to have infusions once a week.
Please review the Instructions for administering Gamunex-C.
Do not receive live vaccines while you are undergoing treatment with Gamunex-C. Talk to your healthcare provider about what vaccines to avoid.
If Gamunex-C is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Gamunex-C with heparin.
The effects of Gamunex-C during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
Gamunex-C should be used under special circumstances determined by your healthcare provider. If you miss your scheduled dose, contact your healthcare provider for advice.
Store in the refrigerator. Do not freeze.
If needed, Gamunex-C can be stored at room temperature for up to 6 months but you must use it within that time or you must throw it away.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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