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  • Generic Name: (altretamine)
    Other Brands: N/A
  • Last Revised: 07/2014
    • What is this medication and its most common uses?

      Hexalen is a medicine used to treat ovarian cancer that has returned after treatment with certain other anticancer medications.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Hexalen is thought to work by slowing or stopping the growth of cancer cells in the body.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: By stopping the growth of cancer cells, Hexalen may help to relieve your symptoms associated with cancer.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider’s directions.

      How do I know it is working?

      Your healthcare provider may order tests regularly to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Hexalen should be prescribed under the supervision of a healthcare provider who is experienced in administering chemotherapy medicines.

      Hexalen can cause brain and nerve problems. Your healthcare provider will monitor you regularly during your treatment with Hexalen.

      Hexalen can also cause low blood cell counts. Your healthcare provider will monitor your blood counts before you begin treatment, as well as every month during your treatment with Hexalen.

      More common side effects may include: nausea, vomiting, tingling in your hands and feet, changes in your mood, problems with coordination, dizziness, low blood cell counts.

      Less common side effects may include:

      Harm to your unborn baby. Tell your healthcare provider immediately if you are pregnant or planning to become pregnant.

    • Who should not take this medication?

      Your healthcare provider will not administer Hexalen to you if you are allergic to it or any of its ingredients.

      Your healthcare provider will not administer Hexalen to you if you have problems with your brain, bone marrow, or nerves.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Hexalen. Also, talk to your healthcare provider about your complete medical history, especially if you have brain or nerve problems, blood problems, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Your healthcare provider will prescribe the appropriate dose for you, based on your height and weight and the type of cancer being treated.

    • How should I take this medication?

      Take Hexalen exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Hexalen without first talking to your healthcare provider.

    • What should I avoid while taking this medication?

      Do not become pregnant while you are taking Hexalen.

      Do not miss any scheduled follow-up appointments with your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      If Hexalen is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Hexalen with the following: cimetidine, a class of medicines known as monoamine oxidase inhibitor (MAOI) (such as phenelzine, selegiline, or linezolid), or pyridoxine.

    • May I receive this medication if I am pregnant or breastfeeding?

      Hexalen can harm your unborn baby if you take it during pregnancy. The effects of Hexalen during breastfeeding are unknown. Do not become pregnant or breastfeed while you are taking Hexalen. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Hexalen, take it as soon as you remember. However, if it is almost time for you next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.