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  • Generic Name: (ifosfamide)
    Other Brands: N/A
  • Last Revised: 11/2014
    • What is this medication and its most common uses?

      Ifex is a medicine used to treat certain types of testicular cancer. Ifex is administered intravenously (directly into a vein).

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Ifex is thought to work by killing cancer cells in the body.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: By killing cancer cells, Ifex may help to relieve your symptoms associated with cancer.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider’s directions.

      How do I know it is working?

      Your healthcare provider may order tests regularly to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Severe, life-threatening myelosuppression (a condition in which the bone marrow activity is decreased, resulting in fewer red blood cells, white blood cells, and platelets) may occur. Your healthcare provider may monitor your blood counts before treatment and during treatment with Ifex.

      Ifex may also cause brain problems. Your healthcare provider may monitor for symptoms such as drowsiness, confusion, hallucinations, blurry vision, involuntary movements, or seizures.

      Ifex may also cause kidney or urinary problems. Ifex may be given with a medicine called mesna to reduce hemorrhagic cystitis (an inflammatory condition of the urinary bladder, resulting in bleeding from the bladder).

      More common side effects may include: hair loss, nausea, vomiting, infection.

      Less common side effects may include:

      Ifex may cause arrhythmias (a life-threatening irregular heartbeat), lung or liver problems, missed menstrual periods, or decreased sperm counts. Ifex may also increase the risk of developing other tumors or interfere with wound healing.

    • Who should not take this medication?

      Your healthcare provider will not administer Ifex to you if you are allergic to it or any of its ingredients.

      Your healthcare provider will not administer Ifex to you if you have a blockage in your urinary flow.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Ifex. Also, talk to your healthcare provider about your complete medical history, especially if you have an infection, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Your healthcare provider will prescribe the appropriate dose for you, based on your height and weight.

    • How should I take this medication?

      Your healthcare provider will administer Ifex to you.

      Ifex is usually administered for 5 straight days.

    • What should I avoid while taking this medication?

      Do not miss any scheduled follow-up appointments with your healthcare provider.

      Do not become pregnant while you are receiving Ifex. Men should not father a child during treatment with Ifex and for up to 6 months after the end of treatment.

    • What are the possible food and drug interactions associated with this medication?

      If Ifex is used with certain other drugs, the effects of either could be increased, decreased, or altered. Ifex may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      Ifex can harm your unborn baby if you receive it during pregnancy, and can be found in your breast milk if you receive it while breastfeeding. Do not breastfeed while you are receiving Ifex. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

       

    • What should I do if I miss a dose of this medication?

      Ifex should be given under special circumstances determined by your healthcare provider. If you miss your scheduled dose, contact your healthcare provider for advice.

    • How should I store this medication?

      Your healthcare provider will store this medication for you.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.