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Impavido is a medicine used to treat certain types of leishmaniasis (a disease caused by certain protozoan parasites) of your organs, skin, nose, mouth, or throat.
How does this medication work?
Impavido is thought to work by stopping the growth of protozoa.
What are the beneficial effects of this medication and when should I begin to have results?
What: In clinical studies, Impavido was shown to significantly cure all lesions.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider’s directions. It is important that you take Impavido exactly as your healthcare provider has prescribed, for the full course of treatment.
How do I know it is working?
You may start to notice an improvement in your symptoms or lesions. This is a good indicator that your medication is working. Your healthcare provider may ask you questions and order tests to assess how well your infection is being treated.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Impavido can cause serious and life-threatening birth defects if taken during pregnancy. Women who can become pregnant should use effective birth control during treatment with Impavido and for 5 months after stopping Impavido treatment. Your healthcare provider will order a pregnancy test before you start your treatment with Impavido. If you become pregnant while taking Impavido, tell your healthcare provider right away.
More common side effects may include: nausea, vomiting, diarrhea, abdominal (stomach area) pain, decreased appetite, dizziness, headache, sleepiness, skin itching.
Less common side effects may include:
Stomach problems with symptoms such as vomiting, diarrhea, or dehydration.
Low platelet (a type of blood cells that form clots to help stop bleeding) counts.
Serious skin problems with symptoms such as a skin rash with blisters.
Impavido may also cause kidney and liver problems.
Do not take Impavido if you are allergic to it or any of its ingredients.
Do not take Impavido if you are pregnant.
Do not take Impavido if you have a condition called Sjogren-Larsson Syndrome.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Impavido. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or liver problems, if you are taking oral contraceptives, or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults and children ≥12 years: Your healthcare provider will prescribe the appropriate dose for you or your child, based on the body weight.
Take Impavido exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Impavido without first talking to your healthcare provider.
Take Impavido capsules whole with food. Do not break, crush, dissolve, or chew the capsules.
Do not skip doses. Skipping doses or not completing the full course of Impavido can decrease its effectiveness.
Do not become pregnant or breastfeed while you are taking Impavido, and for 5 months after stopping treatment with Impavido.
No significant interactions have been reported with Impavido at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.
Impavido can harm your unborn baby if taken during pregnancy. Do not become pregnant or breastfeed while you are taking Impavido. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of Impavido, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature. Protect from moisture.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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