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  • Generic Name: (sitagliptin)
    Other Brands:
  • Last Revised: 04/2016
    • What is this medication and its most common uses?

      Januvia is a medicine used along with diet and exercise to help control high blood sugar in adults with type 2 diabetes.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Januvia helps your pancreas release more insulin and signals the liver to release less sugar, thereby helping to control your blood sugar.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Lowering your blood sugar to a normal level may prevent or delay potential complications associated with diabetes, such as blindness, kidney failure, or heart problems.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Januvia exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Check your blood sugar regularly and as your healthcare provider tells you to. Your healthcare provider will also do regular blood tests to measure your blood sugar levels and your hemoglobin A1C (which estimates your average blood sugar levels over a 2- to 3-month period). Stay on your prescribed diet and exercise program, as this will also affect the results of your blood tests.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: upper respiratory infection, common cold, headache.

      Less common side effects may include:

      Pancreatitis (inflammation of your pancreas) with symptoms such as pain in your abdomen (stomach area) that is severe and will not go away. You may feel the pain going from your abdomen through to your back and may experience vomiting.

      Kidney problems, sometimes requiring dialysis.

      Low blood sugar, especially if you take certain other diabetes medicines. Signs and symptoms of low blood sugar include headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, fast heartbeat, sweating, or feeling jittery.

      Serious allergic reactions with symptoms such as rash; hives; or swelling of your face, lips, tongue, or throat that may cause trouble breathing.

      Januvia may also cause severe joint pain.

    • Who should not take this medication?

      Do not take Januvia if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Januvia. Also, talk to your healthcare provider about your complete medical history, especially if you have pancreatitis, gallstones (stones in your gallbladder), a history of alcoholism, high blood triglyceride (type of fat in the blood) levels, or kidney problems.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended dose is 100 milligrams once a day.

      If you have kidney impairment, your healthcare provider may adjust your dose appropriately.

      If you are also using insulin or taking another diabetes medicine called a sulfonylurea (such as glimepiride, glipizide, or glyburide), your healthcare provider may adjust the dose of these medicines.

    • How should I take this medication?

      Take Januvia exactly as prescribed by your healthcare provider.

      Take Januvia with or without food.

      If your body is under some types of stress (such as a fever, infection, trauma [such as a car accident], or surgery), your healthcare provider may need to adjust the dose of your diabetes medicine.

      While you are taking Januvia, stay on your diet and exercise program, and check your blood sugar regularly as directed by your healthcare provider.

    • What should I avoid while taking this medication?

      Do not change your dose or stop taking Januvia without first talking to your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      If Januvia is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Januvia with digoxin.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Januvia during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

      If you become pregnant while taking Januvia, talk to your healthcare provider about registering with the Januvia pregnancy registry. The purpose of this registry is to collect information about the safety of this medicine during pregnancy.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Januvia, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.