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  • Generic Name: (potassium acid phosphate/sodium acid phosphate anhydrous)
    Other Brands: N/A
  • Last Revised: 12/2014
    • What is this medication and its most common uses?

      K-Phos No. 2 is a medicine used in people with high urinary pH and reduce the odor and rash associated with high ammonia levels in the urine. K-Phos No. 2 is also used to increase the antibacterial activity of methenamine mandelate and methenamine hippurate, when used together.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      K-Phos No. 2 works by acidifying your urine.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: By acidifying the urine, K-Phos No. 2 may help decrease ammonia levels in the urine and increase the effects of certain antibiotics.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take K-Phos No. 2 exactly as your healthcare provider prescribed.

      How do I know it is working?

      You may notice an improvement in your symptoms after you start taking K-Phos No. 2. Your healthcare provider may also order tests regularly and ask you questions from time to time to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Side effects may include: diarrhea; nausea; stomach pain; vomiting; bone or joint pain; irregular heartbeat; dizziness; mental confusion; weakness or heaviness of legs; tiredness; muscle cramps; tingling, numbness, weakness, or pain in the hands, feet, or lips; shortness of breath or trouble breathing; swelling of feet or lower legs; weight gain; decreased urination; thirst.

    • Who should not take this medication?

      Do not take K-Phos No. 2 if you are allergic to it or any of its ingredients.

      Do not take K-Phos No. 2 if you have infected phosphate stones or severe kidney impairment.

      Do not take K-Phos No. 2 if you have high blood phosphorus levels.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with K-Phos No. 2. Also, talk to your healthcare provider about your complete medical history, especially if you have heart failure or problems; severe adrenal insufficiency (a disorder where the body does not make enough of certain hormones), such as Addison's disease (adrenal gland failure); kidney stones or problems; severe burns; myotonia congenital (an inherited muscle disorder); liver problems; leg or feet swelling; fluid retention in the lungs; high blood sodium (salt) level; high blood pressure; preeclampsia (high blood pressure during pregnancy); hypoparathyroidism (underactive parathyroid gland); pancreatitis (inflammation of the pancreas); or if you are dehydrated or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended dose is 1 tablet four times daily. Your healthcare provider may increase your dose as needed, until the desired effect is achieved. Do not take more than 8 tablets within 24 hours.

    • How should I take this medication?

      Take K-Phos No. 2 exactly as prescribed by your healthcare provider. Do not change your dose or stop taking K-Phos No. 2 without first talking to your healthcare provider.

      Take K-Phos No. 2 with a full glass of water.

    • What should I avoid while taking this medication?

      Do not take antacids containing aluminum, calcium, or magnesium.

    • What are the possible food and drug interactions associated with this medication?

      If K-Phos No. 2 is used with certain other drugs, the effects of either could be increased, decreased, or altered. K-Phos No. 2 may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of K-Phos No. 2 during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      The effects of K-Phos No. 2 during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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