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  • Generic Name: (ecallantide)
    Other Brands: N/A
  • Last Revised: 12/2014
    • What is this medication and its most common uses?

      Kalbitor is a medicine used to treat sudden attacks of hereditary angioedema. Kalbitor is administered subcutaneously (just below the skin).

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Kalbitor works by blocking the activity of a protein in the body called plasma kallikrein. In people with hereditary angioedema, the activity of this protein is not controlled properly.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: In studies, patients treated with Kalbitor showed improvement in sudden hereditary angioedema attack symptoms at 4 hours and lasting improvement through 24 hours.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions.

      How do I know it is working?

      You may feel an improvement in your symptoms once you receive Kalbitor. This is a good indicator that your medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Anaphylaxis (a serious and rapid allergic reaction that may result in death if not immediately treated) may occur after Kalbitor administration. Your healthcare provider will administer Kalbitor to you with appropriate medical support to manage symptoms of anaphylaxis. Tell your healthcare provider if you experience shortness of breath, cough, chest tightness, dizziness, fainting, reddening of your face, runny nose, or swelling of your throat.

      Common side effects may include: headache, nausea, diarrhea, fever, injection-site reactions, common cold.

    • Who should not take this medication?

      Your healthcare provider will not administer Kalbitor to you if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Kalbitor. Also, talk to your healthcare provider about your complete medical history.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults and children ≥12 years: Your healthcare provider will prescribe the appropriate dose for you.

    • How should I take this medication?

      Your healthcare provider will administer Kalbitor to you.

      For each dose, you will receive 3 injections just under the skin of your abdomen (stomach area), thigh, or upper arm.

    • What should I avoid while taking this medication?

      Do not attempt to self-administer Kalbitor.

    • What are the possible food and drug interactions associated with this medication?

      No significant interactions have been reported with Kalbitor at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Kalbitor during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      Kalbitor should be given under special circumstances determined by your healthcare provider.

    • How should I store this medication?

      Your healthcare provider will store this medication for you.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.