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Kalbitor is a medicine used to treat sudden attacks of hereditary angioedema. Kalbitor is administered subcutaneously (just below the skin).
How does this medication work?
Kalbitor works by blocking the activity of a protein in the body called plasma kallikrein. In people with hereditary angioedema, the activity of this protein is not controlled properly.
What are the beneficial effects of this medication and when should I begin to have results?
What: In studies, patients treated with Kalbitor showed improvement in sudden hereditary angioedema attack symptoms at 4 hours and lasting improvement through 24 hours.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions.
How do I know it is working?
You may feel an improvement in your symptoms once you receive Kalbitor. This is a good indicator that your medication is working.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Anaphylaxis (a serious and rapid allergic reaction that may result in death if not immediately treated) may occur after Kalbitor administration. Your healthcare provider will administer Kalbitor to you with appropriate medical support to manage symptoms of anaphylaxis. Tell your healthcare provider if you experience shortness of breath, cough, chest tightness, dizziness, fainting, reddening of your face, runny nose, or swelling of your throat.
Common side effects may include: headache, nausea, diarrhea, fever, injection-site reactions, common cold.
Your healthcare provider will not administer Kalbitor to you if you are allergic to it or any of its ingredients.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Kalbitor. Also, talk to your healthcare provider about your complete medical history.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults and children ≥12 years: Your healthcare provider will prescribe the appropriate dose for you.
Your healthcare provider will administer Kalbitor to you.
For each dose, you will receive 3 injections just under the skin of your abdomen (stomach area), thigh, or upper arm.
Do not attempt to self-administer Kalbitor.
No significant interactions have been reported with Kalbitor at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.
The effects of Kalbitor during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
Kalbitor should be given under special circumstances determined by your healthcare provider.
Your healthcare provider will store this medication for you.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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