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  • Generic Name: (insulin glargine (rdna origin))
    Other Brands: N/A
  • Last Revised: 08/2015
    • What is this medication and its most common uses?

      Lantus is a long-acting insulin used to control high blood sugar in people with diabetes. Lantus is available as vials and a prefilled SoloStar pen.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Your body needs insulin to turn sugar into energy. Diabetes develops when your body does not make enough insulin or does not properly use the insulin it makes. Lantus may help control your blood sugar levels by allowing blood sugar to move from your bloodstream into your cells for energy.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Lowering your blood sugar to a normal level may prevent or delay potential complications associated with diabetes, such as blindness, kidney failure, or heart problems. Lantus provides a steady release of insulin to help control blood sugar between meals and overnight for up to 24 hours. Because it works for 24 hours, Lantus is injected just once a day, which may make it easier for you to remember.

      When: Lantus may control your blood sugar levels over the course of a day.

      How do I know it is working?

      Check your blood sugar regularly and as your healthcare provider tells you to. Your healthcare provider will also do regular blood tests to measure your blood sugar levels and your hemoglobin A1C (measures your average blood sugar levels over a 2- to 3-month period). Stay on your prescribed diet and exercise program, as this will also affect the results of your blood tests.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: low blood sugar, injection-site reactions, skin thickening at the injection site, itching, rash, swelling of your hands and feet, weight gain.

      Symptoms of low blood sugar include: dizziness or lightheadedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability or mood changes, or hunger.

      Less common side effects may include:

      Serious and potentially life-threatening allergic reaction, with symptoms such as a rash all over your body, trouble breathing, fast heartbeat, or sweating.

      Lantus may also cause low blood potassium levels.

      Taking certain diabetes pills called thiazolidinediones (such as pioglitazone and rosiglitazone) with Lantus may cause heart failure in some people. This can happen even if you have never had heart failure or heart problems before. If you already have heart failure it may get worse while you take thiazolidinediones with Lantus. Tell your healthcare provider if you have any new or worse symptoms of heart failure including shortness of breath, swelling of your ankles or feet, or sudden weight gain.

    • Who should not take this medication?

      Do not use Lantus if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Lantus. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or liver problems, heart failure or other heart problems, if you are taking a thiazolidinedione, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Type 1 Diabetes

      Adults and children ≥6 years: Inject once a day. Your healthcare provider will prescribe the appropriate dose for you or your child, based on daily insulin requirements.

      Type 2 Diabetes

      Adults: Inject once a day. Your healthcare provider will prescribe the appropriate dose for you, based on your weight.

      Your dose may need to change because of a change in level of physical activity or exercise, weight gain or loss, increased stress, illness, change in diet, or because of the medicines you take.

    • How should I take this medication?

      Inject Lantus exactly as prescribed by your healthcare provider. Do not change the amount of Lantus you inject or stop using it without first talking to your healthcare provider.

      You may inject Lantus at any time during the day, but you must inject it at the same time every day.

      Only use Lantus that is clear and colorless. If your Lantus is cloudy or slightly colored, return it to your pharmacy for a replacement.

      Inject Lantus under the skin of your abdomen (stomach area), upper arm, or upper leg. Do not use Lantus in an insulin pump or inject it into your vein.

      Change your injection site each time you inject Lantus to reduce the chance of developing a reaction.

      Please review the information that comes with your medicine for detailed instructions.

    • What should I avoid while taking this medication?

      Do not share your Lantus SoloStar pen with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.

      Do not reuse needles. Always use a new needle for each Lantus injection.

      Do not mix Lantus with any other type of insulin or liquid medicine.

      Do not drive or operate heavy machinery until you know how Lantus affects you.

      Do not drink alcohol or use over-the-counter medicines that contain alcohol.

    • What are the possible food and drug interactions associated with this medication?

      If Lantus is used with certain other drugs, the effects of either could be increased, decreased, or altered. Lantus may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Lantus during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      It is very important to follow your insulin regimen exactly as prescribed by your healthcare provider. Do not miss any doses. Ask your healthcare provider for specific instructions to follow in case you ever miss a dose of insulin.

    • How should I store this medication?

      Store unopened vials and SoloStar pens in the refrigerator (not the freezer). If they cannot be refrigerated, unopened vials and SoloStar pens may be stored at room temperature for up to 28 days.

      Store open vials in the refrigerator or at room temperature, away from direct heat and light. Open vials must be thrown away 28 days after being opened.

      Store open SoloStar pens at room temperature, away from direct heat and light. Open SoloStar pens must be thrown away 28 days after being opened.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.