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Macrodantin is an antibiotic used to treat urinary tract infections.
How does this medication work?
Macrodantin works by killing bacteria, thereby treating your infection. Macrodantin does not treat viral infections, such as the common cold.
What are the beneficial effects of this medication and when should I begin to have results?
What: Macrodantin has been shown to be effective against various types of bacteria that can cause a urinary tract infection.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Macrodantin exactly as your healthcare provider has prescribed for the full course of treatment, even if your symptoms improve earlier.
How do I know it is working?
You may start to notice an improvement in your symptoms. This is a good indicator that your medication is working. Your healthcare provider may ask you questions and order tests to assess how well your infection is being treated.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: allergic reactions, nausea, vomiting, loss of appetite.
Less common side effects may include:
Life-threatening lung problems, especially if you receive therapy for six months or longer, with symptoms such as fever, chills, cough, chest pain, or shortness of breath.
Liver problems, with symptoms such as unexplained nausea or vomiting, stomach pain, fever, weakness, tenderness, itching, unusual tiredness, loss of appetite, light-colored bowel movements, dark-colored urine, or yellowing of your skin or the whites of your eyes.
Watery and bloody stools (with or without stomach cramps and fever), even as late as two or more months after having taken the last dose of Macrodantin.
Macrodantin may also cause peripheral neuropathy (numbness, pain, or tingling in your hands or feet) or optic neuritis (inflammation of the optic nerve that causes blurring, graying, or loss of vision).
Do not take Macrodantin if you are allergic to it or any of its ingredients.
Do not take Macrodantin if you have anuria (inability to produce urine), oliguria (do not produce enough urine), or kidney problems.
Do not take Macrodantin if you are at the end of your pregnancy (38-42 weeks).
Do not take Macrodantin if you have experienced liver problems or yellowing of your skin or the whites of your eyes with previous treatment with nitrofurantoin (main ingredient in Macrodantin).
Do not give Macrodantin to newborn babies <1 month of age.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Macrodantin. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney, liver, or lung problems; anemia (low red blood cell counts); diabetes; glucose-6-phosphate dehydrogenase (G6PD) deficiency (lack of an enzyme responsible for the breakdown of red blood cells); or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The recommended dose is 50 to 100 milligrams four times a day.
Children ≥1 month: Your healthcare provider will prescribe the appropriate dose for your child, based on his/her weight.
Your healthcare provider may adjust your or your child's dose, depending on your needs.
Take Macrodantin exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Macrodantin without first talking to your healthcare provider.
Take Macrodantin with food.
Do not skip doses. Skipping doses or not completing the full course of Macrodantin can decrease its effectiveness and can lead to the growth of bacteria that are resistant to the effects of Macrodantin.
If Macrodantin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Macrodantin with the following: antacids containing magnesium trisilicate, probenecid, or sulfinpyrazone.
The effects of Macrodantin during pregnancy are unknown. Macrodantin can be found in your breast milk if you take it while breastfeeding. Do not breastfeed while you are taking Macrodantin. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of Macrodantin, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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