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  • Generic Name: (megestrol acetate)
    Other Brands: Megace
  • Last Revised: 09/2014
    • What is this medication and its most common uses?

      Megace ES is a medicine used to treat loss of appetite, cachexia (malnutrition), or unexplained weight loss in people with acquired immunodeficiency syndrome (AIDS).

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      It is unknown exactly how Megace ES works to increase appetite.

      Megace ES is not used to prevent weight loss.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Studies have shown that Megace ES improved appetite and increased caloric intake.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Megace ES exactly as your healthcare provider has prescribed.

      How do I know it is working?

      You may notice an improvement in your appetite after you start taking Megace ES. Your healthcare provider may also ask you questions from time to time to assess how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: nausea, diarrhea, impotence (inability to achieve and maintain an erection), rash, gas, high blood pressure, weakness.

      Less common side effects may include:

      Harm to your unborn baby if taken during pregnancy. Contact your healthcare provider immediately if you believe or suspect you are pregnant while you are taking Megace ES.

      Adrenal insufficiency (a disorder where the body does not make enough of certain hormones), with symptoms such low blood pressure, nausea, vomiting, dizziness, or weakness.

      Megace ES may also cause or worsen existing diabetes.

       

    • Who should not take this medication?

      Do not take Megace ES if you are allergic to it or any of its ingredients.

      Do not take Megace ES if you are pregnant or think you may be pregnant.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Megace ES. Also, talk to your healthcare provider about your complete medical history, especially if you have diabetes, Cushing's syndrome (a hormone disorder), adrenal gland problems, bleeding problems, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended starting dose is 625 milligrams (5 milliliters) once a day.

    • How should I take this medication?

      Take Megace ES exactly as prescribed by your healthcare provider. Do not change your dose without first talking to your healthcare provider.

      Shake the bottle well before taking your dose of Megace ES.

    • What should I avoid while taking this medication?

      Do not become pregnant or breastfeed while you are taking Megace ES.

    • What are the possible food and drug interactions associated with this medication?

      If Megace ES is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Megace ES with the following: indinavir.

    • May I receive this medication if I am pregnant or breastfeeding?

      Megace ES can harm your unborn baby if taken during pregnancy. Do not become pregnant or breastfeed while you are taking Megace ES. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Megace ES, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature. Protect from heat.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.