PDR MEMBER LOGIN:
  • Required field
  • Generic Name: (methadone hydrochloride)
    Other Brands: N/A
  • Last Revised: 05/2015
    • What is this medication and its most common uses?

      Methadone intensol oral concentrate is a medicine used to treat moderate to severe around the clock pain. It is also used in conjunction with appropriate social and medical support to treat and manage drug addiction.

      Methadone intensol oral concentrate is a federally controlled narcotic with potential for abuse.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Methadone intensol oral concentrate works in your central nervous system (the brain and spinal cord) and affects the way your body responds to pain and addiction.

      Methadone intensol oral concentrate is not used to treat pain that you only have now and then ("as needed"), or after surgery if the pain is mild or not expected to last for a long period.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Methadone intensol oral concentrate may help to relieve pain and to manage drug addiction.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take methadone intensol oral concentrate exactly as your healthcare provider has prescribed.

      How do I know it is working?

      You may feel an improvement in your pain or withdrawal symptoms. This is a good indicator that the medicine is working. Your healthcare provider may also ask you questions from time to time to assess how well your symptoms are controlled with treatment.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Methadone intensol oral concentrate has abuse, addiction, and misuse potential. This can lead to overdose and other life threatening problems. If you have concerns, talk to your healthcare provider for more information about abuse and addiction. Do not share methadone intensol oral concentrate with others and take steps to protect methadone intensol oral concentrate from theft or misuse.

      Serious, life-threatening breathing problems may occur when taking methadone intensol oral concentrate, especially at treatment initiation and when the dose is increased. Tell your healthcare provider right away if you have trouble breathing; shortness of breath; fast heartbeat; chest pain; swelling of your face, tongue, or throat; extreme drowsiness; or feel faint.

      Methadone intensol oral concentrate may cause life-threatening changes in the electrical activity of your heart. Tell your healthcare provider if you have symptoms such as chest pain, fast or slow heartbeat, shortness of breath, and dizziness or fainting.

      Keep methadone intensol oral concentrate in a safe place away from children. Accidental use may result in serious harm and may be life-threatening.

      When used for drug addiction, methadone intensol oral concentrate is available only through certified opioid treatment programs. If you have questions, talk to your healthcare provider for more information about these programs.

      More common side effects may include: lightheadedness, dizziness, sleepiness, nausea, vomiting, sweating.

      Less common side effects may include:

      Sudden fall in your blood pressure with symptoms such as dizziness, lightheadedness, or fainting when rising too quickly from a sitting or lying position.

    • Who should not take this medication?

      Do not take methadone intensol oral concentrate if you are allergic to it or any of its ingredients.

      Do not take methadone intensol oral concentrate if you are having an asthma attack, or if you have severe asthma, trouble breathing, or other lung problems.

      Do not take methadone intensol oral concentrate if you have a bowel blockage or narrowing of your stomach or intestines.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescriptions, over-the-counter, and herbal medications you are taking before beginning treatment with methadone intensol oral concentrate. Also, talk to your healthcare provider about your complete medical history, especially if you have a head injury; seizures; problems urinating; pancreas or gallbladder problems; mental health problems; lung or breathing problems; heart, liver, kidney, or thyroid problems; a history of alcohol or drug abuse; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Treatment of Pain

      Adults: The usual starting dose is 2.5 every 8 or 12 hours around the clock for your first dose. Your healthcare provider may give you additional doses and adjust your dose as needed based on any previous pain medication and the type and severity of your pain.

      Drug Addiction

      Adults: Your healthcare provider will give you 20 to 30 mg for your first dose. Your healthcare provider may give you additional doses and adjust your dose as needed.

      If you have liver or kidney impairment, your healthcare provider may adjust your dose appropriately.

      It is important that you do not stop taking this medication abruptly. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.

    • How should I take this medication?

      Take methadone intensol oral concentrate exactly as prescribed by your healthcare provider. Do not change your dose or stop taking methadone intensol oral concentrate without first talking to your healthcare provider.

      When you stop taking methadone intensol oral concentrate, flush any unused methadone intensol oral concentrate down the toilet. 

    • What should I avoid while taking this medication?

      Do not drive a car, operate heavy machinery, or engage in other dangerous activities until you know how methadone intensol oral concentrate affects you.

      Do not drink alcohol or take prescription or over-the-counter medicines that contain alcohol while you are taking methadone intensol oral concentrate.

    • What are the possible food and drug interactions associated with this medication?

      If methadone intensol oral concentrate is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Methadone intensol oral concentrate may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      Prolonged use of methadone intensol oral concentrate during pregnancy can cause withdrawal symptoms in your newborn baby that could be life-threatening if not recognized or treated. Methadone intensol oral concentrate can be found in breast milk if you take it during breastfeeding. If you take methadone intensol oral concentrate while you are breastfeeding, check your baby for increased sleepiness, difficulty feeding, trouble breathing, or limpness. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you take methadone intensol oral concentrate for pain and miss a dose, take it as soon as you remember. Then take your next dose 8 or 12 hours later as directed by your healthcare provider. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once or more than your prescribed dose in 24 hours.

      If you take methadone intensol oral concentrate for drug addiction and miss a dose, take your next dose the following day as scheduled. Do not take extra doses.

    • How should I store this medication?

      Store at room temperature. Protect from light.

    • Who should I contact in case of emergency or overdose?
      back to top

      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
  •  
  • Terms of Service

    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.