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Naglazyme is a medicine used to treat Mucopolysaccharidosis VI (MPS VI, Maroteaux-Lamy syndrome) (a rare genetic disease caused by a deficiency of a certain enzyme). Naglazyme is administered intravenously (through a vein in your arm).
How does this medication work?
Naglazyme replaces the enzyme that is lacking in people with MPS VI.
What are the beneficial effects of this medication and when should I begin to have results?
What: Naglazyme has been shown to improve walking and stair-climbing ability.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider’s directions.
How do I know it is working?
Your healthcare provider may order tests regularly to check how well this medication is working.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: rash, pain, hives, fever, itching, chills, headache, nausea, vomiting, stomach area pain, difficulty breathing.
Less common side effects may include:
Serious and life-threatening allergic reactions with symptoms such as difficulty breathing, wheezing, swelling of the throat, and low blood pressure.
Your healthcare provider will not administer Naglazyme to you if you are allergic to it or any of its ingredients.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Naglazyme. Also, talk to your healthcare provider about your complete medical history, especially if you have lung or breathing problems (such as sleep apnea [stopping breathing temporarily during sleep]), heart problems, or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults and children: Your healthcare provider will prescribe the appropriate dose for you or your child, based on the body weight.
Your healthcare provider will administer Naglazyme to you.
Do not miss any scheduled follow-up appointments with your healthcare provider.
No significant interactions have been reported with Naglazyme at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.
The effects of Naglazyme during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
Naglazyme should be given under special circumstances determined by your healthcare provider. If you miss your scheduled dose, contact your healthcare provider or pharmacist for advice.
Your healthcare provider will store this medication for you.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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