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Namenda XR is a medicine used to treat moderate to severe dementia (an illness involving confusion, loss of memory, and impaired judgment) in people with Alzheimer's disease.
How does this medication work?
Namenda XR is an extended-release medicine (a type of capsule that releases medicine into your body throughout the day). It works by decreasing abnormal activity in the brain, thereby helping to improve your symptoms of Alzheimer‘s disease.
What are the beneficial effects of this medication and when should I begin to have results?
What: When used with another Alzheimer's medicine known as an acetylcholinesterase inhibitor (such as donepezil, galantamine, or rivastigmine), Namenda XR has been shown to improve the ability to perform activities of daily living, as well as help with cognition, which includes elements of attention, memory, and social interaction.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Namenda XR exactly as your healthcare provider has prescribed.
How do I know it is working?
You or your caregiver may notice an improvement in your condition. Your healthcare provider may ask you or your caregiver a series of questions from time to time that will help assess how well your symptoms are controlled with treatment.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: headache, diarrhea, dizziness.
Less common side effects may include:
Certain medical conditions may affect the amount of Namenda XR in your body and possibly increase the risk of side effects. Talk to your healthcare provider if you have renal tubular acidosis (a disease that occurs when the kidneys fail to excrete acids into the urine, which causes a person's blood to remain too acidic) or a severe urinary tract infection.
Do not take Namenda XR if you are allergic to it or any of its ingredients.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Namenda XR. Also, talk to your healthcare provider about your complete medical history, especially if you have liver or kidney problems.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The recommended starting dose is 7 milligrams once a day. Your healthcare provider may increase your dose as needed, until the desired effect is achieved.
If you have severe kidney impairment, your healthcare provider may adjust your dose appropriately.
Take Namenda XR exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Namenda XR without first talking to your healthcare provider.
Take Namenda XR with or without food.
Namenda XR capsules can be swallowed whole or may be opened, sprinkled on applesauce and the entire contents swallowed.
Except when opened and sprinkled on applesauce, swallow Namenda XR capsules whole. Do not crush, divide, or chew the capsules.
Do not divide the dose of Namenda XR when you sprinkle the contents of the capsule on applesauce. Swallow the entire contents of the capsule with the applesauce.
If Namenda XR is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Namenda XR with the following: amantadine, carbonic anyhydrase inhibitors (such as acetazolamide or methazolamide), cimetidine, dextromethorphan, hydrochlorothiazide, ketamine, metformin, nicotine, quinidine, ranitidine, or sodium bicarbonate.
The effects of Namenda XR during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a single dose of Namenda XR, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
If you miss several doses of Namenda XR, contact your healthcare provider before taking your next dose.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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