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  • Generic Name: (donepezil hydrochloride/memantine hydrochloride)
    Other Brands: N/A
  • Last Revised: 09/2016
    • What is this medication and its most common uses?

      Namzaric is a medicine used to treat moderate to severe dementia in people with Alzheimer's disease.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Namzaric contains two medicines that work in 2 different ways to treat Alzheimer's disease: donepezil and memantine. Donepezil is thought to work by slowing the breakdown of a chemical in the brain called acetylcholine (a chemical involved in learning and memory). Memantine may help regulate the abnormal activity of glutamate (another chemical in the brain that is important for learning and memory).

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Namzaric has been shown to improve mental function as well as overall function.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. It is important that you take Namzaric exactly as your healthcare provider has prescribed.

      How do I know it is working?

      You or your caregiver may notice an improvement in your condition. Your healthcare provider may also ask you or your caregiver questions from time to time to assess how well your symptoms are controlled with treatment.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects of memantine may include: headache, diarrhea, dizziness.

      More common side effects of donepezil may include: diarrhea, loss of appetite, vomiting, nausea, bruising.

      Less common side effects of Namzaric may include:

      Heart problems with symptoms such as slow heartbeat and fainting.

      Increased stomach acid production, which may increase the risk of stomach ulcers and bleeding. The risk is higher for people who had ulcers or take aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) (such as ibuprofen or naproxen).

      Namzaric may also cause seizures or difficulty passing urine.

    • Who should not take this medication?

      Do not take Namzaric if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Namzaric. Also, talk to your healthcare provider about your complete medical history, especially for any of the following: heart problems (including an irregular, slow, or fast heartbeat); asthma or lung problems; seizures; stomach ulcers; bladder or kidney problems; liver problems; if you have surgical, dental, or other medical procedures scheduled where anesthesia may be used; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended dose is one capsule once a day, in the evening.

    • How should I take this medication?

      Take Namzaric exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Namzaric without first talking to your healthcare provider.

      Take Namzaric with or without food.

      Namzaric capsules may be opened and sprinkled on applesauce before swallowing. Sprinkle all of the medicine in the capsule on the applesauce. Do not divide the dose.

      If you do not open and sprinkle Namzaric capsules on applesauce, the capsules must be swallowed whole. Do not divide, chew, or crush the capsules.

    • What should I avoid while taking this medication?

      Do not use any Namzaric capsules that are damaged or show signs of tampering.

    • What are the possible food and drug interactions associated with this medication?

      If Namzaric is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Namzaric may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Namzaric during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Namzaric, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.