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  • Generic Name: (sonidegib)
    Other Brands: N/A
  • Last Revised: 06/2016
    • What is this medication and its most common uses?

      Odomzo is a medicine used to treat a type of skin cancer, called basal cell carcinoma, that has come back following surgery or radiation or that cannot be treated with surgery or radiation.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Odomzo works by blocking the action of a protein that signals cancer cells to multiply, which in turn may slow down the growth of your basal cell carcinoma.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Odomzo may cause your basal cell carcinoma to shrink, or it may help control your disease.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. It is important that you take Odomzo exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may order certain tests to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Odomzo can harm an unborn baby or cause severe birth defects if taken during pregnancy. You should talk to your healthcare provider about the risks of Odomzo to your unborn child. Your healthcare provider will do a pregnancy test before you start taking Odomzo. Women should use birth control during treatment and for at least 20 months after the last dose of Odomzo.

      It is not known if Odomzo is present in semen. Men should always use a condom, even if they had a vasectomy, during sex with female partners who are pregnant or who are able to become pregnant, during treatment with Odomzo and for at least 8 months after the final dose to protect their female partner from being exposed to Odomzo.

      Common side effects may include: muscle spasms, hair loss, changes in taste, tiredness, nausea, muscle or bone pain, diarrhea, weight loss, decreased appetite, abdominal (stomach area) pain, headache, pain, vomiting, itching.

    • Who should not take this medication?

      Do not take Odomzo if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Odomzo. Also, talk to your healthcare provider about your complete medical history, especially if you have muscle pain or spasms, a history of a muscle disorder called rhabdomyolysis or myopathy, or are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended dose is 200 milligrams once a day.

    • How should I take this medication?

      Take Odomzo exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Odomzo without first talking with your healthcare provider.

      Take Odomzo on an empty stomach, at least 1 hour before or 2 hours after a meal.

    • What should I avoid while taking this medication?

      Do not donate blood or blood products while you are taking Odomzo and for 20 months after your last dose.

      Do not donate semen while taking Odomzo and for at least 8 months after your last dose.

    • What are the possible food and drug interactions associated with this medication?

      If Odomzo is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Odomzo may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      Odomzo can harm an unborn baby if taken during pregnancy. Women should use birth control during treatment and for at least 20 months after the last dose of Odomzo. Men should always use condoms, even if they have had a vasectomy, during sex with female partners who are pregnant or who are able to become pregnant, during treatment with Odomzo and for at least 8 months after the last dose. It is not known if Odomzo passes into breast milk. Do not breastfeed during treatment and for 20 months after your last dose of Odomzo. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

      If you become pregnant while taking Odomzo, you or your healthcare provider should report your pregnancy to Novartis Pharmaceuticals Corporation.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Odomzo, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.