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  • Generic Name: (bromocriptine mesylate)
    Other Brands: N/A
  • Last Revised: 06/2014
    • What is this medication and its most common uses?

      Parlodel is a medicine used to treat symptoms associated with hyperprolactinemia (an increase in a hormone called prolactin that can affect lactation, menstruation, and fertility). It is also used to treat certain tumors associated with prolactin. Parlodel is also used to treat acromegaly (a condition in which there is too much growth hormone in the body) and Parkinson's disease. Parlodel is available as tablets and capsules.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Symptoms of Parkinson's disease may occur when there is a decrease in dopamine in the brain. Parlodel works by increasing dopamine levels in the brain. It also lowers levels of prolactin and growth hormone in the body.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Parlodel may help to relieve symptoms associated with hyperprolactinemia, acromegaly, or Parkinson's disease.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Parlodel exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may ask you a series of questions from time to time that will help assess how well your symptoms are controlled with treatment. Your healthcare provider may also order tests regularly to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Hyperprolactinemia

      More common side effects may include: nausea, headache, dizziness.

      Acromegaly

      More common side effects may include: nausea, constipation, sudden drop in blood pressure, loss of appetite, mouth or nasal stuffiness, indigestion.

      Parkinson's Disease

      More common side effects may include: nausea, abnormal involuntary movements, hallucinations, confusion, dizziness, drowsiness, fainting, vomiting, lack of strength, abdominal (stomach area) discomfort, visual disturbance, problems with coordination, trouble sleeping, depression, low blood pressure, shortness of breath, constipation, a spinning feeling.

      Less common side effects of Parlodel may include:

      Changes in your behavior, including intense urges to gamble, increased sexual urges, or other intense urges.

      Parlodel may also cause high blood pressure, seizures, or a heart attack.

    • Who should not take this medication?

      Do not take Parlodel if you are allergic to it, any of its ingredients, or to similar medicines known as ergot alkaloids (such as dihydroergotamine).

      Do not take Parlodel if you have uncontrolled high blood pressure.

      Do not take Parlodel if you are pregnant or plan to become pregnant without first checking with your healthcare provider.

      Do not take Parlodel if you have a history of heart disease or other heart problems and you recently gave birth.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Parlodel. Also, talk to your healthcare provider about your complete medical history, especially if you have high blood pressure, a history of mental or heart problems, lactose intolerance (trouble digesting dairy products), trouble digesting sugar, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Hyperprolactinemia

      Adults and children 11-15 years: The usual starting dose is one-half to one 2.5-milligram (mg) tablet a day.

      Acromegaly

      Adults: The usual starting dose is one-half to one 2.5-mg tablet at bedtime for 3 days.

      Parkinson's Disease

      Adults: The usual starting dose is one-half of a 2.5 mg-tablet twice a day.

      Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

      It is important that you do not stop taking this medication abruptly. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.

    • How should I take this medication?

      Take Parlodel exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Parlodel without first talking to your healthcare provider.

      Take Parlodel with food.

      If you are taking Parlodel for hyperprolactinemia and you experience persistent watery or runny nose, notify your healthcare provider.

      Your healthcare provider may recommend a pregnancy test at least every 4 weeks during the absence of a menstrual cycle period. Always follow your healthcare provider's instructions.

    • What should I avoid while taking this medication?

      Do not drink alcohol while taking Parlodel without first checking with your healthcare provider.

      Do not drive, operate heavy machinery, or do other dangerous activities until you know how Parlodel affects you.

    • What are the possible food and drug interactions associated with this medication?

      If Parlodel is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Parlodel may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Parlodel during pregnancy are unknown. Do not breastfeed while you are taking Parlodel. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Parlodel, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.