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Quinidine is a medicine used to restore normal heart rhythm in people with atrial fibrillation (an irregular, fast heartbeat) and to reduce the frequency of atrial fibrillation. Quinidine is also used to suppress ventricular arrhythmias (a certain type of life-threatening irregular heartbeat). Quinidine is an extended-release medicine (a type of tablet that releases medicine into your body throughout the day).
How does this medication work?
Quinidine works by changing the electrical activity of the heart, thereby regulating your heart rhythm.
What are the beneficial effects of this medication and when should I begin to have results?
What: Quinidine may help to make your heart beat more regularly.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take quinidine exactly as your healthcare provider has prescribed.
How do I know it is working?
Your healthcare provider may order tests regularly to check how well this medication is working.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Quinidine may increase your risk of life-threatening effects.
More common side effects may include: diarrhea, nausea, vomiting, heartburn.
Less common side effects may include:
New or worsened abnormal heartbeats that can be life-threatening.
Quinidine may also cause low platelet (a type of blood cell that forms clots to help stop bleeding) counts.
Do not take quinidine if you are allergic to it or any of its ingredients.
Do not take quinidine if you previously developed thrombocytopenic purpura (a condition in which blood clots form in the blood vessels and can occur all over the body) to quinidine or to another medicine called quinine.
Do not take quinidine if your heart rhythm depends on a certain type of pacemaker.
Do not take quinidine if you previously experienced a side effect with medicines known as anticholinergics (such as ipratropium).
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with quinidine. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney, heart, or liver problems; congestive heart failure (a condition in which the heart cannot pump enough blood throughout the body); sick sinus syndrome (abnormal heart rhythm); or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: Your healthcare provider will prescribe the appropriate dose for you, and may adjust the dose as needed.
Take quinidine exactly as prescribed by your healthcare provider. Do not change your dose or stop taking quinidine without first talking to your healthcare provider.
Do not chew or crush quinidine tablets without first checking with your healthcare provider. Chewing or crushing the tablets may prevent the medicine from releasing into your body throughout the day.
Do not drink grapefruit juice while you are taking quinidine.
If quinidine is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Quinidine may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.
The effects of quinidine during pregnancy are unknown. Quinidine can be found in your breast milk if you take it while breastfeeding. Do not breastfeed while you are taking quinidine. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of quinidine, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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