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Ravicti is a medicine used along with a low protein diet to manage high blood levels of ammonia caused by a condition called urea cycle disorder. Ravicti is available as an oral liquid. Ravicti may also be administered through a feeding tube.
How does this medication work?
Ravicti works by removing ammonia from the body.
What are the beneficial effects of this medication and when should I begin to have results?
What: People treated with Ravicti experienced average blood ammonia levels within a normal range during the treatment year.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. It is important that you take Ravicti exactly as your healthcare provider has prescribed.
How do I know it is working?
Your healthcare provider may order certain tests to check your blood ammonia levels.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: diarrhea, gas, headache.
Less common side effects may include:
Nervous system problems, with symptoms such as sleepiness, weakness, lightheadedness, changes in taste, hearing or memory problems, confusion, worsening numbness or tingling in your hands or feet, or headache.
Do not take Ravicti if you are allergic to it or any of its ingredients.
Do not give Ravicti to children <2 months of age.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Ravicti. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or liver problems, pancreas or bowel (intestine) problems, or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults and children ≥2 years: Your healthcare provider will prescribe the appropriate dose for you based on your condition or previous medicine, and may adjust the dose as needed.
If you have liver impairment, your healthcare provider may adjust your dose appropriately.
Take Ravicti exactly as prescribed by your healthcare provider.
Take Ravicti with food.
Administer Ravicti directly into the mouth with an oral syringe or a dosing cup.
Do not change your dose or stop taking Ravicti without first talking to your healthcare provider.
If Ravicti is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Ravicti with the following: alfentanil, corticosteroids (such as prednisone), cyclosporine, haloperidol, midazolam, probenecid, quinidine, or valproic acid.
The effects of Ravicti during pregnancy and breastfeeding are unknown. Do not breastfeed while you are taking Ravicti. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you become pregnant while taking Ravicti, talk to your healthcare provider about registering with the pregnancy registry associated with Ravicti. The purpose of this registry is to collect information about the health of you and your baby.
If you miss a dose of Ravicti, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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