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  • Generic Name: (antihemophilic factor (recombinant))
    Other Brands: N/A
  • Last Revised: 09/2014
    • What is this medication and its most common uses?

      Recombinate is a medicine used to prevent and control bleeding episodes in people with hemophilia A (a type of bleeding disorder). It is also used to prevent bleeding during surgical procedures in people with hemophilia A. Recombinate is administered intravenously (directly into your vein).

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Recombinate works by replacing a clotting factor in your body, thereby helping your blood to form clots and decreasing bleeding episodes.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: By replacing a clotting factor in your body, Recombinate has been shown to treat bleeding episodes in people with hemophilia A.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider’s directions. It is important that you use Recombinate exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may perform certain tests to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: chills, flushing, rash, nose bleeds.

      Less common side effects may include:

      Allergic reactions, with symptoms such as dizziness, itching, rash, hives, flushing, face swelling, difficulty breathing, paleness, fever, nausea, low blood pressure, tingling or numbness of your hands or feet, or loss of consciousness.

    • Who should not take this medication?

      Do not use Recombinate if you are allergic to it or any of its ingredients.

      Do not use Recombinate if you are allergic to mouse, hamster, or cow proteins.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Recombinate. Also, talk to your healthcare provider about your complete medical history, especially if you have been told that you have inhibitors to Factor VIII (because Recombinate may not work for you).

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults and children: Your healthcare provider will prescribe the appropriate dose for you or your child, based on the type of surgery or condition being treated.

    • How should I take this medication?

      Use Recombinate exactly as prescribed by your healthcare provider. Do not use it more often or stop using it without first talking to your healthcare provider.

      After reconstituting, administer Recombinate within 3 hours. Do not refrigerate after reconstituting.

      Please review the instructions from your healthcare provider regarding how to properly administer Recombinate. It is recommended to use the administration set provided.

    • What should I avoid while taking this medication?

      Do not attempt to self-infuse Recombinate unless you have been taught how by your healthcare provider or hemophilia center.

    • What are the possible food and drug interactions associated with this medication?

      No significant interactions have reported with Recombinate at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Recombinate during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      Recombinate should be used under special circumstances determined by your healthcare provider. If you miss your scheduled dose, contact your healthcare provider or pharmacist for advice.

    • How should I store this medication?

      Store in the refrigerator or at room temperature. Do not freeze.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.