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  • Generic Name: (mirtazapine)
    Other Brands: N/A
  • Last Revised: 10/2016
    • What is this medication and its most common uses?

      Remeron is a medicine used to treat depression.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Remeron is thought to work by increasing the activity of certain chemicals in your brain, thereby helping to improve your symptoms of depression.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Remeron has been shown to relieve symptoms of depression, as measured by appropriate symptom rating scales that are commonly used by healthcare providers to evaluate the effectiveness of the medicine in people with this condition. Remeron has also been shown to lower the rates of depression relapse.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. It is important that you take Remeron exactly as your healthcare provider has prescribed, even if you do not feel better right away.

      How do I know it is working?

      You may feel an improvement in your depression after you start taking Remeron. This is a good indicator the medicine is working. Your healthcare provider may also ask you questions from time to time that will help assess how well your symptoms are controlled with treatment.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Remeron may increase suicidal thoughts or actions in some children, teenagers, or young adults within the first few months of treatment or when a dose is changed. Your healthcare provider will monitor you closely for clinical worsening and suicidal or unusual behavior. Call your healthcare provider right away if you experience anxiety, agitation, panic attacks, trouble sleeping, irritability, hostility, aggressiveness, impulsive behavior, an increase in activity or talking more than what is normal for you, or other unusual change in behavior or mood during treatment with Remeron.

      More common side effects may include: drowsiness, increased appetite, weight gain, dizziness.

      Less common side effects may include:

      Decreased white blood cells, which are needed to fight infections. Symptoms of an infection may include fever, chills, sore throat, or mouth or nose sores.

      Serotonin syndrome (a potentially life-threatening drug reaction that causes the body to have too much serotonin, a chemical produced by the nerve cells) with symptoms such as mental status changes (such as agitation or hallucinations), a racing heartbeat, high or low blood pressure, sweating or fever, coordination problems or muscle twitching, muscle stiffness, nausea, vomiting, or diarrhea.

      Vision problems with symptoms such as eye pain, changes in vision, or swelling or redness in or around the eye. Only some people are at risk for visual problems. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are.

      Low sodium (salt) levels in the blood, with symptoms such as headache, weakness or feeling unsteady, confusion, problems concentrating or thinking, or memory problems. Elderly people may be at greater risk for this.

      Manic episodes with symptoms such as greatly increased energy, severe trouble sleeping, racing thoughts, reckless behavior, excessive happiness or irritability, talking more or faster than usual, or unusually grand ideas.

      Remeron may also cause akathisia (a condition characterized by restlessness or an inability to sit or stand still), increased cholesterol and triglyceride (type of fat in the blood) levels, or seizures.

    • Who should not take this medication?

      Do not take Remeron if you are allergic to it or any of its ingredients.

      Do not take Remeron if you take another medicine called a monoamine oxidase inhibitor (MAOI) (such as phenelzine, selegiline, or linezolid), a class of medications used to treat depression and other conditions. Do not start taking Remeron if you stopped taking an MAOI in the last 2 weeks.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Remeron. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or liver problems, heart problems or a certain condition that may change your heart rhythm, seizures or convulsions, bipolar disorder or mania, or a tendency to get dizzy or faint; or if you are pregnant, breastfeeding, or planning to become pregnant.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended starting dose is 15 milligrams once a day. Your healthcare provider may increase your dose as needed, until the desired effect is achieved.

      It is important that you do not stop taking this medication abruptly. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.

    • How should I take this medication?

      Take Remeron exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Remeron without first talking to your healthcare provider.

      Take Remeron in the evening at bedtime.

      Remeron may be taken with or without food.

    • What should I avoid while taking this medication?

      Do not drive, operate heavy machinery, or do other dangerous activities until you know how Remeron affects you.

      Do not drink alcohol or take diazepam (a medicine used for anxiety, insomnia, and seizures) or similar medicines while taking Remeron. If you are uncertain about whether a certain medication can be taken with Remeron, discuss it with your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      If Remeron is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Remeron may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Remeron during pregnancy are unknown. Remeron may be found in your breast milk if you take it while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Remeron, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature. Protect from light and moisture.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.