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Requip is a medicine used to treat Parkinson's disease and restless legs syndrome.
How does this medication work?
Dopamine is a natural chemical in the brain that helps control movement. Requip is thought to increase the activity of dopamine, thereby improving motor control.
What are the beneficial effects of this medication and when should I begin to have results?
Parkinson's Disease: Studies show that people who receive Requip have significantly greater improvement in motor function (such as decreased muscle rigidity) than people who do not receive Requip.
Restless Legs Syndrome: Requip has been shown to reduce the severity of symptoms, sleep disturbances, daytime drowsiness, and impact on activities of daily living, as measured by appropriate symptom rating scales that are commonly used by healthcare providers to evaluate the effectiveness of the medicine in people with such conditions.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Requip exactly as your healthcare provider has prescribed.
How do I know it is working?
Your healthcare provider may ask you a series of questions from time to time, which will help assess how well your symptoms are controlled with treatment.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Early Parkinson's Disease
More common side effects may include: nausea, dizziness, drowsiness, vomiting, fainting, infection, leg swelling, upset stomach, weakness.
Advanced Parkinson's Disease
More common side effects may include: uncontrollable muscle movements, nausea, dizziness, confusion, drowsiness, headache, hallucinations, sweating.
Restless Legs Syndrome
More common side effects may include: nausea, drowsiness, vomiting, dizziness, weakness.
Less common side effects of Requip may include:
Falling asleep while doing normal activities such as driving a car, doing physical tasks, or using hazardous machinery. You may suddenly fall asleep without being drowsy or without warning. Your chances of falling asleep while doing normal activities while taking Requip are greater if you are also taking other medicines that cause drowsiness.
Sudden fall in blood pressure when first standing up from sitting or lying down, especially when you start taking Requip or when your healthcare provider increases your dose, with symptoms such as dizziness, nausea, faintness, or sweating.
Urges to behave in a way unusual for you, such as unusual urges to gamble or increased sexual urges and behaviors.
If you are also taking L-dopa for Parkinson's disease, Requip may make some side effects of L-dopa worse, such as causing uncontrolled sudden movements or make such movement you already have worse.
Requip may increase or decrease your heart rate.
Requip can cause or worsen psychotic-like behavior including hallucinations (seeing or hearing things that are not real), confusion, excessive suspicion, aggressive behavior, agitation, delusional beliefs (believing things that are not real), and disorganized thinking.
People with Parkinson's disease have a higher risk of melanoma (type of skin cancer). It is not clear if this risk is associated with the disease or with the medicines to treat it. Your healthcare provider may check your skin on regular basis.
Do not take Requip if you are allergic to it or any of its ingredients.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Requip. Also, talk to your healthcare provider about your complete medical history, especially if you have liver or heart problems, changes in your blood pressure, daytime sleepiness from a sleep disorder other than restless legs syndrome, if you start or stop smoking, drink alcoholic beverages, or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The recommended starting dose is 0.25 milligrams (mg) three times a day.
Adults: The recommended starting dose is 0.25 mg once a day, 1 to 3 hours before bedtime.
If you have kidney impairment and are receiving dialysis, your healthcare provider may start you on a different dose.
Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.
People with restless legs syndrome take Requip differently than people with Parkinson's disease. Therefore, it is very important that you take Requip exactly as prescribed by your healthcare provider. Do not change your dose or suddenly stop taking Requip without first talking to your healthcare provider.
Take Requip with or without food.
Do not drive a car, operate machinery, or engage in other dangerous activities if you fall asleep or feel very sleepy after taking Requip.
If Requip is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Requip may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.
The effects of Requip during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of Requip, contact your healthcare provider.
Store at room temperature. Protect from light and moisture.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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