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  • Generic Name: (octreotide acetate)
    Other Brands: N/A
  • Last Revised: 08/2016
    • What is this medication and its most common uses?

      Sandostatin LAR is a medicine for people in whom initial treatment with immediate-release Sandostatin injection has been shown to be effective and tolerated for:

      • Long-term maintenance therapy in people with acromegaly (a condition in which there is too much growth hormone in the body) who have had inadequate response to surgery and/or radiotherapy or for whom surgery and/or radiotherapy is not an option
      • Long-term treatment of the severe diarrhea and flushing episodes associated with carcinoid tumors (slow-growing cancerous tumors that sometimes produce hormones that can cause symptoms known as carcinoid syndrome) that have spread throughout the body
      • Long-term treatment of the profuse watery diarrhea associated with vasoactive intestinal peptide tumors (a cancer that usually grows from cells in the pancreas)

      Sandostatin LAR is administered intramuscularly (injected into the muscle) by a healthcare provider.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Sandostatin LAR works by decreasing the amount of certain natural substances produced by the body, thereby improving your condition.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: By decreasing levels of growth hormone and other hormones, Sandostatin LAR may help improve acromegaly and symptoms associated with carcinoid tumors and vasoactive intestinal peptide tumors.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions.

      How do I know it is working?

      You may feel an improvement in your symptoms once you begin receiving Sandostatin LAR. This is a good indicator that the medication is working. Your healthcare provider may also ask you questions to assess how well your symptoms are controlled.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects in people with acromegaly may include: diarrhea, gallstones, abdominal (stomach-area) pain, gas.

      More common side effects in people with carcinoid syndrome may include: back pain, tiredness, headache, abdominal pain, nausea, dizziness.

      Less common side effects of Sandostatin LAR may include:

      Sandostatin LAR may affect gallbladder function, sugar metabolism, thyroid and heart function, and nutritional absorption, which may require monitoring by your healthcare provider.

    • Who should not take this medication?

      Your healthcare provider will not administer Sandostatin LAR to you if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Sandostatin LAR. Also, talk to your healthcare provider about your complete medical history, especially if you have diabetes; or kidney, liver, gallbladder, heart, or thyroid problems.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Your healthcare provider will prescribe the appropriate dose for you.

      If you have kidney or liver impairment, your healthcare provider may adjust your dose appropriately.

    • How should I take this medication?

      Your healthcare provider will administer Sandostatin LAR to you.

    • What should I avoid while taking this medication?

      Do not miss any scheduled follow-up appointments with your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      If Sandostatin LAR is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Sandostatin LAR with the following: blood pressure/heart medications known as beta-blockers (such as metoprolol or propranolol), bromocriptine, cyclosporine, insulin, oral diabetes medicines, quinidine, or terfenadine.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Sandostatin during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      Sandostatin LAR should be used under special circumstances determined by your healthcare provider. If you miss your scheduled dose, contact your healthcare provider for advice.

    • How should I store this medication?

      Your healthcare provider will store this medication for you.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.