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  • Generic Name: (ixekizumab)
    Other Brands: N/A
  • Last Revised: 04/2016
    • What is this medication and its most common uses?

      Taltz is a medicine used to treat plaque psoriasis (a disorder in which skin grows and replaces itself too rapidly, causing a buildup of red, thickened areas [plaques] covered with silvery scales). Taltz is administered subcutaneously (just below the skin).

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Taltz works by blocking the action of a protein in the body that causes inflammation, thereby helping to reduce inflammation and improve symptoms.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Taltz may help clear or almost clear symptoms associated with plaque psoriasis, such as redness, thickness, or scaling of the skin.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you use Taltz exactly as your healthcare provider has prescribed.

      How do I know it is working?

      You may notice an improvement in your symptoms after you start using Taltz. This is a good indicator that the medicine is working. Your healthcare provider may ask you questions to assess how well your symptoms are controlled.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: upper respiratory infection, injection site reactions, nausea, fungal infections.

      Less common side effects may include:

      Serious allergic reactions, with symptoms such as feeling faint; swelling of your face, eyelids, tongue, or throat; trouble breathing or throat tightness; chest tightness; or skin rash.

      Taltz may increase your risk of getting Crohn's disease (an inflammatory disease of the digestive track) or ulcerative colitis (inflammatory bowel disease) with symptoms such as stomach pain, diarrhea with or without blood, and weight loss.

    • Who should not take this medication?

      Do not use Taltz if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Taltz. Also, talk to your healthcare provider about your complete medical history, especially if you have Crohn's disease or ulcerative colitis, tuberculosis (a bacterial infection that affects the lungs), or if you have recently received or are scheduled to receive an immunization (vaccine).

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended dose is 160 milligrams (mg) (two 80 mg injections) at Week 0, followed by 80 mg at Weeks 2, 4, 6, 8, 10, and 12, then 80 mg every 4 weeks.

    • How should I take this medication?

      Use Taltz exactly as prescribed by your healthcare provider. Do not use it more often or stop using it without first talking to your healthcare provider.

      If your healthcare provider decides that you or a caregiver may give your injections of Taltz at home, you should receive training on the right way to prepare and inject Taltz.

      Taltz comes in an autoinjector and a prefilled syringe that you or your caregiver may use at home to give injections. Your healthcare provider will decide which type of Taltz is best for you to use at home.

      Administer each injection at a different location (such as upper arms, thighs, or stomach area) than the previous injection. Do not inject into areas where the skin is tender, bruised, or red, or in an area of skin that is affected by psoriasis.

      Please review the instructions that came with your prescription on how to properly inject and dispose of Taltz.

    • What should I avoid while taking this medication?

      Do not try to inject Taltz yourself until your healthcare provider has shown you how to inject it appropriately.

      Do not receive any live vaccines. Talk to your healthcare provider about what vaccines to avoid.

      Do not shake Taltz or use if the liquid is discolored or cloudy.

    • What are the possible food and drug interactions associated with this medication?

      If Taltz is used with certain other drugs, the effects of either could be increased, decreased, or altered. Taltz may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Taltz during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Taltz, inject it as soon as you remember and return to your regular dosing schedule. Do not inject two doses at once.

    • How should I store this medication?

      Store in the refrigerator. Do not freeze. Protect from light.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.