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Tarka is a medicine used to treat high blood pressure. Tarka contains two medicines that work in two different ways to reduce your blood pressure: trandolapril and verapamil.
How does this medication work?
Tarka is an extended-release medicine, which releases medicine into your body throughout the day. Tarka works by blocking a chemical in your body that causes blood vessels to narrow. By blocking this chemical, Tarka relaxes and widens your blood vessels, allowing your blood to flow through with less resistance. This helps to lower your blood pressure.
What are the beneficial effects of this medication and when should I begin to have results?
What: By lowering your blood pressure, Tarka may lower your risk of a stroke or a heart attack.
When: Tarka may start lowering your blood pressure within 1 week. Though you may not feel an improvement or change in the way you feel, it is very important to keep taking your medicine as prescribed to keep your condition under control.
How do I know it is working?
Check your blood pressure regularly. Your healthcare provider may also check your blood pressure at every visit. Following an appropriate diet and exercise plan will also affect your blood pressure results.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Tarka can harm your unborn baby. Talk to your healthcare provider about other ways to lower your blood pressure if you plan to become pregnant. Tell your healthcare provider right away if you become pregnant while taking Tarka.
More common side effects may include: heart block, constipation, cough, dizziness.
Less common side effects may include:
Liver problems, with symptoms such as tiredness, fever, and/or right upper abdominal (stomach area) pain.
Serious allergic reactions, with symptoms such as rash, hives, trouble swallowing or breathing, and swelling of your face, lips, tongue, or throat.
Tarka may also cause heart failure, excessively low blood pressure, and low white blood cell counts.
Do not take Tarka if you are allergic to it or any of its ingredients, or if you have a history of angioedema (a condition involving swelling of the face, extremities, eyes, lips, and tongue) related to previous treatment with similar medicines.
Do not take Tarka if you have severe left ventricular dysfunction (impairment of a section of your heart that is responsible for pumping blood to the rest of your body).
Do not take Tarka if you have low blood pressure.
Do not take Tarka if you have sick sinus syndrome (abnormal heart rhythm) or a heart block, unless you have a pacemaker.
Do not take Tarka if you have atrial fibrillation or flutter (an irregular, fast heartbeat) and certain heart conduction problems (such as Wolff-Parkinson-White or Lown-Ganong-Levine syndromes).
Do not take Tarka if you have diabetes and are taking another blood pressure medicine called aliskiren.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Tarka. Also, talk to your healthcare provider about your complete medical history, especially if you have diabetes, kidney or liver problems, a heart condition, or a disease that affects your immune system (such as lupus or scleroderma); are scheduled to have surgery; or are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: Your healthcare provider will prescribe the appropriate dose for you based on your previous blood pressure medication, and may adjust your dose as needed, until the desired effect is achieved.
If you have kidney or liver problems, your healthcare provider may adjust your dose appropriately.
Take Tarka exactly as prescribed by your healthcare provider.
Take Tarka with food.
Do not change your dose or stop taking Tarka without first talking to your healthcare provider.
If Tarka is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Tarka may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.
Do not take Tarka if you are pregnant or breastfeeding. Tarka may harm your unborn baby if taken during pregnancy, and may pass into your breast milk if taken while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of Tarka, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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