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Uptravi is a medicine used to treat pulmonary arterial hypertension (high blood pressure in the arteries of the lungs).
How does this medication work?
Uptravi may help open up blood vessels in the lungs allowing blood to flow more easily.
What are the beneficial effects of this medication and when should I begin to have results?
What: Uptravi may help slow down the progression of your disease and lower your risk of being hospitalized.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. It is important that you take Uptravi exactly as your healthcare provider has prescribed.
How do I know it is working?
You may notice an improvement in your symptoms once you begin taking Uptravi. This is a good indicator that your medicine is working. Your healthcare provider may also ask you questions from time to time to assess how well your condition is controlled.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Common side effects may include: headache, diarrhea, jaw pain, nausea, muscle pain, vomiting, pain in your arms or legs, flushing (warm, hot, burning feeling to your face).
Do not take Uptravi if you are allergic to it or any of its ingredients.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Uptravi. Also, talk to your healthcare provider about your complete medical history, especially if you have liver problems, narrowing of your pulmonary veins (a condition called pulmonary veno-occlusive disease), or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The recommended starting dose is 200 micrograms twice a day. Your healthcare provider may increase your dose as needed, until the desired effect is achieved.
If you have liver impairment, your healthcare provider may adjust your dose appropriately.
Take Uptravi exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Uptravi without first talking to your healthcare provider.
Do not split, crush, or chew Uptravi tablets.
If Uptravi is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Uptravi may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.
The effects of Uptravi during pregnancy and breastfeeding are unknown. Do not breastfeed while you are taking Uptravi. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of Uptravi, take it as soon as you remember. However, if the next dose is within the next 6 hours, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
If you miss treatment for 3 days or more, call your healthcare provider.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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