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  • Generic Name: (ursodiol)
    Other Brands: N/A
  • Last Revised: 12/2014
    • What is this medication and its most common uses?

      Urso is a medicine used to treat primary biliary cirrhosis (a condition in which the bile ducts in your liver are slowly destroyed, causing scarring of your liver). Urso is available as Urso 250 and Urso Forte.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      When bile ducts are damaged, harmful substances may build up in your liver. Urso is a bile acid (a substance naturally produced by the body that is stored in the gallbladder) and works by replacing harmful substances.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Urso may help to improve the condition of your liver.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. It is important that you take Urso exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider will monitor your liver function on a monthly basis at the start of therapy.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Common side effects may include: abdominal (stomach area) discomfort or pain, hair loss, diarrhea, nausea, itching, rash.

    • Who should not take this medication?

      Do not take Urso if you are allergic to it or any of its ingredients.

      Do not take Urso if you have biliary obstruction.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Urso. Also, talk to your healthcare provider about your complete medical history.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Your healthcare provider will prescribe the appropriate dose for you, based on your weight, and may adjust the dose as needed.

    • How should I take this medication?

      Take Urso exactly as prescribed by your healthcare provider.

      Take Urso with food.

      Urso Forte tablets are scored and can be broken in half. Do not use segments that are broken incorrectly. Swallow the segments with water. Keeping the segments in the mouth can reveal a bitter taste. Store segments separately from whole tablets.

    • What should I avoid while taking this medication?

      Do not change your dose or stop taking Urso without first talking to your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      If Urso is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Urso with the following: antacids containing aluminum, birth control pills, certain cholesterol-lowering medicines (such as clofibrate), cholestyramine, colestipol, or estrogens.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Urso during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Urso, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.