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Varubi is a medicine used in combination with other medicines to help prevent nausea and vomiting that may happen several days after receiving chemotherapy.
How does this medication work?
Varubi works by blocking the action of natural chemicals in the brain that cause nausea and vomiting.
What are the beneficial effects of this medication and when should I begin to have results?
What: When taken with other medicines, Varubi has been shown to prevent nausea and vomiting caused by chemotherapy.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Varubi exactly as your healthcare provider has prescribed.
How do I know it is working?
You may notice you are no longer experiencing nausea and vomiting after you receive chemotherapy. This is a good indicator that your medicine is working. Your healthcare provider may also ask you questions from time to time to check how well your symptoms are controlled with treatment.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Patients Receiving Cisplatin Chemotherapy Medicine
More common side effects may include: Low white blood cell count, hiccups.
Patients Receiving Anthracycline and Cyclophosphamide Chemotherapy Medicines
More common side effects may include: Decreased appetite, low white blood cell count, dizziness.
Less common side effects may include:
Serious or life-threatening reactions, including heart rhythm changes, if used with certain other medicines.
Do not take Varubi if you are allergic to it or any of its ingredients.
Do not take Varubi if you take a medicine called thioridazine.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Varubi. Also, talk to your healthcare provider about your complete medical history, especially if you have liver problems, are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: On Day 1 of chemotherapy, take 2 Varubi tablets about 1-2 hours before you receive chemotherapy. Your healthcare provider will tell you how and when to take your other medications.
Take Varubi exactly as prescribed by your healthcare provider.
Do not take Varubi more than one time every 14 days.
Varubi can be taken with or without food.
Do not miss any scheduled follow-up appointments with your healthcare provider.
If Varubi is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Varubi may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.
The effects of Varubi during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
Varubi should be taken under special circumstances determined by your healthcare provider. If you miss your scheduled dose, contact your healthcare provider or pharmacist for advice.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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