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  • Generic Name: (mecamylamine hydrochloride)
    Other Brands: N/A
  • Last Revised: 12/2015
    • What is this medication and its most common uses?

      Vecamyl is a medicine used to treat moderately severe to severe high blood pressure. Vecamyl can also be used in hospital settings for high blood pressure emergencies.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Vecamyl works by blocking the action of certain chemicals in your body, thereby lowering your blood pressure.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: By lowering your blood pressure, Vecamyl may lower your risk of a heart attack or stroke.

      When: Vecamyl may start to lower your blood pressure within 30 minutes to 2 hours. Though you may not feel an improvement or change in the way you feel, it is very important to keep taking this medication as prescribed to keep your condition under control.

      How do I know it is working?

      Check your blood pressure regularly. Your healthcare provider may also check your blood pressure at every visit. Following an appropriate diet and exercise plan will also affect your blood pressure results.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: blurred vision, constipation, dizziness, nausea, vomiting, weakness.

      Less common side effects may include:

      Central nervous system effects, such as shaking, rapid or jerky movements, or seizures.

      Vecamyl may also cause urinary retention (an inability to empty the bladder completely); dizziness, lightheadedness, or fainting, especially when rising from a lying or sitting position; or frequent loose bowel movements.

    • Who should not take this medication?

      Do not take Vecamyl if you are allergic to it or any of its ingredients.

      Do not take Vecamyl if you have certain heart problems (including a recent heart attack), glaucoma (high pressure in the eye), uremia (urea in the blood), or pyloric stenosis (narrowing of the opening from the stomach into the small intestine).

      Do not take Vecamyl if you are taking certain antibiotics or sulfonamides (such as sulfamethoxazole).

      Your healthcare provider may not prescribe Vecamyl to you if you have certain kidney problems.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Vecamyl. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or heart problems, reduced blood flow to the brain, prostate or bladder problems or problems passing urine, fever or infection, bleeding problems, if you are on a salt-restricted diet, if you plan to undergo surgery, if you drink alcohol, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The usual starting dose is one 2.5-milligram tablet twice a day. Your healthcare provider may increase your dose as needed, until the desired effect is achieved.

      It is important that you do not stop taking this medication abruptly. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.

    • How should I take this medication?

      Take Vecamyl exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Vecamyl without first talking to your healthcare provider.

      Take Vecamyl consistently, either with or without food.

      If you experience frequent loose bowel movements with abdominal (stomach area) pain, stop taking the medicine and notify your healthcare provider immediately.

    • What should I avoid while taking this medication?

      Do not become exposed to excessive heat or engage in vigorous exercise without first checking with your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      If Vecamyl is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Vecamyl with the following: alcohol, certain antibiotics or sulfonamide medicines, or other blood pressure medications (such as lisinopril or valsartan).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Vecamyl during pregnancy are unknown. Do not breastfeed while you are taking Vecamyl. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Vecamyl, take it as soon as your remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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