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  • Generic Name: (coagulation factor VIII complex (human)/von Willebrand factor (human))
    Other Brands: N/A
  • Last Revised: 03/2016
    • What is this medication and its most common uses?

      Wilate is a medicine used to treat bleeding in people with von Willebrand disease (VWD). Wilate is also used to prevent bleeding during and after surgery in people with VWD. Wilate is administered intravenously (through a vein in your arm).

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Wilate works by temporarily replacing a clotting factor in your body that is needed to help stop bleeding.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Wilate may help to control your bleeding episodes.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. It is important that you use Wilate exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may perform certain tests to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: allergic reactions, hives, dizziness.

      Less common side effects may include:

      Wilate may transmit disease or cause allergic reactions because it is made from human blood, or may increase the risk of developing blood clots.

    • Who should not take this medication?

      Do not use Wilate if you are allergic to it, any of its ingredients, or to human-derived products.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Wilate. Also, talk to your healthcare provider about your complete medical history, especially if you have been told that you have antibodies to FVIII and VWF.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults and children: Your healthcare provider will prescribe the appropriate dose for you based on your weight and the type of bleeding you have.

    • How should I take this medication?

      Use Wilate exactly as prescribed by your healthcare provider.

      Wilate is administered as an infusion into your vein after reconstitution of the lyophilized powder by mixing it with the supplied 5 or 10 milliliter sterile solvent with the supplied transfer device. Please review the instructions that come with your prescription on how to properly administer Wilate.

      Your healthcare provider may instruct you on how to do reconstitutions and infusions using sterile technique on your own or with the help of a family member. Carefully follow your healthcare provider's instructions regarding the dose and schedule so that your treatment will work the best that it can.

      Reconstitute the powder only directly before injection. Use the solution immediately after reconstitution and throw away any remaining solution.

      Contact your healthcare provider right away if bleeding is not controlled after using Wilate.

      Talk to your healthcare provider before traveling. Plan to bring enough Wilate for your treatment during this time.

    • What should I avoid while taking this medication?

      Do not use Wilate more often or stop using it without first talking to your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      No significant interactions have been reported with Wilate at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Wilate during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Wilate, do not use two doses to make up for the forgotten dose. Proceed with the next infusion as scheduled.

    • How should I store this medication?

      Store in the refrigerator for up to 36 months from the date of manufacture. Within this period, may store for up to 6 months at room temperature. Do not return to the refrigerator if stored at room temperature.

      Store in the original container to protect from light. Do not freeze.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.