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  • Generic Name: (miglustat)
    Other Brands: N/A
  • Last Revised: 03/2016
    • What is this medication and its most common uses?

      Zavesca is a medicine used to treat Gaucher disease (a condition in which a certain fatty substance is not broken down normally in the body).

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Zavesca works by reducing the buildup of fatty substances, thereby improving your condition.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: In studies, Zavesca has been shown to provide important benefits (such as reducing swelling of certain organs) for people with Gaucher disease.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Zavesca exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may perform certain tests to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Common side effects may include: diarrhea, weight loss, stomach pain, gas, nausea, vomiting, headache, shaking, leg cramps, dizziness, weakness, vision problems, low platelet (a type of blood cell that forms clots to help stop bleeding) counts, muscle cramps, back pain, constipation, dry mouth, heaviness in arms and legs, memory loss, unsteady walking, loss of appetite, indigestion, tingling or numbness of your hands or feet, stomach bloating, stomach pain not related to food, menstrual changes.

    • Who should not take this medication?

      Do not take Zavesca if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zavesca. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney problems, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended dose is one 100-milligram capsule three times a day.

      Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

      If you have kidney impairment, your healthcare provider may adjust your dose appropriately.

    • How should I take this medication?

      Take Zavesca exactly as prescribed by your healthcare provider. Do not change your dose or stop taking it without first talking to your healthcare provider.

      Take Zavesca at regular intervals.

    • What should I avoid while taking this medication?

      Do not eat foods high in carbohydrates if you are experiencing diarrhea with treatment. Discuss with your healthcare provider about your diet if you experience diarrhea.

    • What are the possible food and drug interactions associated with this medication?

      No significant interactions have been reported with Zavesca at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Zavesca during pregnancy and breastfeeding are unknown. Do not breastfeed while you are taking Zavesca. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Zavesca, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.