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Zebutal is a medicine used to treat tension headaches. Zebutal contains three medicines that work in three different ways to relieve your headache: acetaminophen, butalbital, and caffeine.
How does this medication work?
Zebutal is thought to work by changing the way your body responds to pain.
What are the beneficial effects of this medication and when should I begin to have results?
What: Zebutal may help relieve your tension headaches.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Zebutal exactly as your healthcare provider has prescribed.
How do I know it is working?
You may feel a relief in your tension headache after you take Zebutal. This is a good indicator that the medicine is working. Recording your headache frequency and medication use may be helpful to you and your healthcare provider in monitoring your progress.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Acetaminophen (a component of Zebutal) can cause serious, life-threatening liver problems. The risk of liver problems may be increased in people who have existing liver disease or drink alcohol while taking Zebutal. Do not take more than 4000 milligrams (mg) of acetaminophen a day or take more than one product that contains acetaminophen. Contact your healthcare provider right away if you took more than 4000 mg of acetaminophen in a day.
More common side effects may include: drowsiness, lightheadedness, dizziness, shortness of breath, nausea, vomiting, abdominal (stomach area) pain, intoxicated feeling.
Less common side effects may include:
Serious allergic reactions, with symptoms such as a rash, hives, itching, vomiting, trouble breathing, or swelling of your face, mouth, or throat.
Zebutal has abuse potential. If you have concerns, talk to your healthcare provider for more information about abuse and addiction.
Zebutal may also cause serious skin reactions.
Do not take Zebutal if you are allergic to it or any of its ingredients.
Do not take Zebutal if you have porphyria (a genetic disease that causes intermittent attacks of stomach pain and neurological [brain, nerves, and spine] symptoms).
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zebutal. Also, talk to your healthcare provider about your complete medical history, especially if you have liver, kidney, or stomach problems; or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults and children ≥12 years: The recommended dose is 1 or 2 capsules every 4 hours as needed. Do not take more than 6 capsules in one day.
Take Zebutal exactly as prescribed by your healthcare provider. Do not change your dose without first talking to your healthcare provider.
Do not drive a car, operate heavy machinery, or engage in other activities that require you to be alert until you know how Zebutal affects you.
Do not drink alcohol or take prescription or over-the-counter medicines that contain alcohol while you are taking Zebutal.
Do not take more than 4000 mg of acetaminophen a day. To avoid taking more than the recommended dose, be sure not to take other prescription or over-the-counter products that contain acetaminophen.
If Zebutal is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Zebutal with the following: alcohol, antidepressant medications known as monoamine oxidase inhibitors (MAOIs) (such as phenelzine or tranylcypromine), narcotic painkillers (such as morphine or oxycodone), other medicines that may make you sleepy (such as alprazolam or triazolam), or tranquilizers (such as chlordiazepoxide).
The effects of Zebutal during pregnancy are unknown. Zebutal can be found in your breast milk if taken while breastfeeding. Do not breastfeed while you are taking Zebutal. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
Zebutal should be taken only as needed for tension headaches.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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