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Zemaira is a medicine used for long-term treatment in people who have emphysema (a lung disease that causes shortness of breath) caused by a severe alpha1-proteinase inhibitor deficiency. Zemaira is administered intravenously (directly into a vein).
How does this medication work?
Alpha1-proteinase inhibitor is a certain protein that works to protect the lungs and liver. In people who do not have enough of this protein, Zemaira works to replace the deficient protein in your body.
What are the beneficial effects of this medication and when should I begin to have results?
What: Zemaira may help to provide protection to the lower respiratory tract by correcting the deficiency.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions.
How do I know it is working?
You may feel an improvement in your symptoms. Your healthcare provider may order tests regularly to check how well this medication is working.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: headache, sinusitis (sinus pain and congestion), upper respiratory infection, bronchitis (inflammation of the air passages within the lungs), weakness, increased cough, fever, bleeding at the injection site, runny nose, sore throat, relaxing of the blood vessels.
Less common side effects may include:
Serious allergic reactions, with symptoms such as rash; hives; swelling of the face, mouth, and tongue; or breathing problems.
Zemaira may also transmit infections because it is made from human blood.
Your healthcare provider will not administer Zemaira to you if you are allergic to it or any of its ingredients.
Your healthcare provider will not administer Zemaira to you if you have immunoglobulin A deficiency.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zemaira. Also, talk to your healthcare provider about your complete medical history, especially if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: Your healthcare provider will prescribe the appropriate dose for you, based on your body weight.
Your healthcare provider will administer Zemaira for you.
Do not miss any follow-up appointments with your healthcare provider.
No significant interactions have been reported with Zemaira at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.
The effects of Zemaira during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
Zemaira should be given under special circumstances determined by your healthcare provider. If you miss your scheduled dose, contact your healthcare provider or pharmacist for advice.
Your healthcare provider will store this medication for you.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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