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  • Mie Collagen + Probiotics Nourish the Skin from Within


    DIETARY SUPPLEMENT

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    Mie Collagen + Probiotics
    Nourish the Skin from Within

    Dietary Supplement

    Rejuvenate yourself with Mie Collagen + Probiotics your self-care superpowder. Clinical studies show that youthful skin and a healthy gut are interconnected.

    The professional grade collagen peptides help improve your skin integrity with increased hydration, moisture and elasticity. Meanwhile, seven complementary probiotics balance your inner microbiome and strengthen your dermatological health.

    Professional Grade Collagen Peptides

    • Hydrolyzed bovine collagen peptides Type I and III to help minimize the visible effects of aging1
    • Enhanced with Hyaluronic Acid, Vitamin C, Biotin and Copper to maximize health for skin, hair and nails1
    • 15 minutes rapid absorption using clinically tested Collagen Absorbing Technology

    1
    These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    Proprietary Blend of Probiotics

    • Developed with Korean probiotic technology clinically shown to have anti-wrinkle and skin moisturizing properties1
    • Seven (7) complementary strains for achieving gut wellness, including a proprietary strain of Lactobacillus plantarum
    • Seventeen (17) billion CFUs of friendly gut bacteria help with improved immunity and balanced digestion1
    Supplement Facts
    Serving Size 1 Packet (4g)
    Servings Per Container 14
    Amount Per Serving % DV*
    *
    Percent Daily Values are based on a 2,000 calorie diet.
    Daily Value not established.
    Calories 12
    Sodium 10mg 0%
    Protein 3g 6%
    Calcium 7mg 1%
    Biotin 5000mcg 16,670%
    Copper (as Copper Gluconate) 0.45mg 50%
    Vitamin C (as Ascorbic Acid) 80mg 90%
    Hydrolyzed Collagen Peptides 2.5g
    Hyaluronic Acid 100mg
    Pomegranate fruit extract 25mg
    PURE Proprietary Probiotic Blend
    17 Billion CFU as input
      Lactobacillus plantarum (HY7714)
      Bifidobacterium lactis
      Lactobacillus acidophilus
      Bifidobacterium longum
      Bifidobacterium breve
      Lactobacillus casei
      Streptococcus thermophilus

    Other ingredients: Citric acid, Natural flavors (Lemon, Raspberry, Green Apple), Stevia, Beet root powder (color), rice hulls

    Recommended Use

    Mix one packet daily with 8 fl. oz. of cold water. Stir well or shake. Delicious over ice or served in a smoothie.

    Keep in a cool, dry place. Avoid direct sunlight.

    Not recommended for use in children. If you are pregnant, nursing or have a medical condition, consult your physician before use.

    How supplied 14 Stick Packets: 4g (0.14oz.), Net Wt. 56g (1.97oz)

    Developed for and Distributed by LivePURE
    7164 Technology Drive, Suite 100
    Frisco, TX 75033

    Livepure.com

    Our Promise

    • 100% PURE
    • Hormone Free
    • Grass Fed
    • Free Range
    • No Gluten
    • No GMOs
    • No Carbs
    • No Sugar
    • No Preservatives
    • No Additives
    • No Artificial Flavors
    • No Antibiotics

    Ingredients

    Biotin

    Biotin is an essential B complex vitamin (B7) that supports metabolism (making energy from food) and is a primary component of healthy hair, skin, and nails.1

    Collagen Peptides

    Collagen is the most abundant protein in the body. It is a primary component of connective tissues that make up tendons and ligaments of the body's joints and is found in the muscles and skin. Collagen provides structure and firmness to these body components. As time progresses, collagen production within the body diminishes, which impacts skin, bone and joint health. After the age of twenty, the body makes 1% less collagen each year. By age 40, a person makes 20% less collagen than they made at age 20. Most collagen proteins found in other collagen products require additional digestion for the body to effectively utilize it. By adding professional-grade, hydrolyzed collagen peptides to your daily routine, you can increase the production of collagen within the body.1

    Copper

    Copper is an essential mineral that participates in connective tissue synthesis, which is necessary to produce certain proteins in the body such as collagen. It is also a critical component of one of the body's internal antioxidant systems called superoxide dismutase (SOD). So, in addition to dietary sources of antioxidants, the body makes its own antioxidants and copper is necessary for the creation of these internal antioxidants.1

    Vitamin C

    Widely known for its antioxidant properties, vitamin C is also essential for the creation of collagen within the body. It is critically important for making connective tissue, which makes it vital for skin and joint health. Adequate levels of vitamin C are needed to maintain the health of the skin's dermis (outer) and epidermis (inner) layers.1

    Hyaluronic Acid

    Also called hyaluronan, hyaluronic acid (HA) is a protein substance naturally made within the body. It can be found within the connective tissues of the joints, skin, and the eyes. It helps bind together these living connective tissues. It helps maintain skin hydration and helps facilitate smooth movement of the joints. HA has been shown in clinical research to support good skin health and beauty. Like collagen, as a person ages the amount of HA they make diminishes.1

    Pomegranate

    Pomegranate (Punica granatum L.), considered an ancient fruit and superfruit, is cultivated in west Asia, the Mediterranean, and the United States. The word pomegranate in both Arabic and Hebrew means "fruit of paradise." Its traditional use is steeped in both medicine and spirituality. Used as a natural remedy, all parts of the fruit are rich in phytonutrient polyphenols known for their antioxidant functions. Pomegranate also contributes to the delicious flavor of Mie Collagen + Probiotics.1

    Lactobacillus plantarum Probiotic

    Lactobacillus plantarum (HY7714) is a novel, first to the US market probiotic strain developed in Korea. It promotes healthier looking skin for a more youthful appearance. In clinical trial, study participants who supplemented with Lactobacillus plantarum (HY7714) saw significant improvements in skin hydration and a minimization of fine lines and wrinkles of the face.1

    Bifidobacterium lactis, Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium breve, Lactobacillus casei, and Streptococcus thermophilus Probiotics.

    In addition to their skin health benefits, these probiotics support a healthy digestive tract and immune system. Different Lactobacillus and Bifidobacterium species have been shown to promote a positive mood and healthy outlook on life. The use of probiotics may also support a healthy cardiovascular system by helping to maintain existing healthy cholesterol and blood pressure levels.1

    Frequently Asked Questions

    What does Mie mean and how do you pronounce it?

    "Me" (spelled Mei) means beautiful in Korean and Chinese. The LivePURE product spelled Mie is pronounced as me (mē or mee).

    Why should I take collagen?

    Collagen is a primary component of connective tissues that make up tendons and ligaments of the body's joints. It is also found in the muscles and skin. Koll the root of collagen is the Greek word for glue. Collagen provides structure, firmness and elasticity to all connective tissues within the body. After the age of 20, the body makes 1% less collagen each year. By age 40, a person makes 20% less collagen than they did at age 20. As a result of this gradual loss of collagen, there is a structural decrease in skin firmness, the emergence of wrinkles, and reduced performance of joints and muscles. Collagen added to the diet supports the body's ability to replenish normal age-related collagen loss. Collagen's anti-aging effects include improved skin health, beauty, joint mobility and muscle performance.**

    What are collagen peptides?

    Collagen is hard, fibrous, insoluble (does not mix well in liquid) and poorly absorbed by the body. Collagen peptides are purified (broken down into a simpler form) from collagen making it more easily digestible and absorbed by the body. Not all collagen peptides are the same. Mie Collagen + Probiotics uses a uniquely processed hydrolyzed collagen peptides, which are highly dissolvable when added to water. Live Pure calls this proprietary process C.A.T.™ or collagen absorption technology. The use of this proprietary technology helps ensure the rapid and thorough absorption of the collagen peptides.1

    What is C.A.T.™ – Collagen Absorption Technology?

    C.A.T. is a proprietary, science-based delivery technology that maximizes the absorption of collagen. The collagen peptides used in Mie Collagen + Probiotics are more easily absorbed and digested by the body, because they have been optimized for solubility and dissolution. Something that dissolves well in water is considered soluble. A common reason for poor absorption and bioavailability of other collagen products is their lack of solubility. Scientific research on absorption of hydrolyzed collagen peptides has demonstrated their presence in the blood within 15 minutes of consuming them making them a more efficient form of collagen.1

    Why do I need to take a probiotic product?

    Parts of the digestive tract consists of good and bad bacteria. The connection between a healthy digestive tract bacteria and overall good health is extraordinarily strong. A growing body of scientific evidence has shown that good digestive tract health is connected to how well the immune system responds to foreign invaders, our brain health, mood, digestive health, skin health and the list continues to grow. The standard American diet – SAD (highly processed and high in sugar foods), the overuse of antibiotics, drinking too much alcohol, stress, cigarette smoking, a lack of exercise and inadequate sleep are all disruptors of good bacteria. Taking a high-quality probiotic supplement helps promote a healthy balance of good digestive tract bacteria.1

    Why should I take collagen and probiotics together?

    There are many benefits to taking a high-quality collagen peptide supplement. These benefits include an improvement in joint and muscle performance and a more youthful appearance. Anecdotally, health practitioners often recommend collagen to improve digestive tract health, which is a primary benefit of taking probiotics. A growing body of scientific evidence has shown that probiotics can help improve the skin's appearance, especially the clinically tested and patented probiotic strain from Korea HY7714 (from Lactobacillus plantarum). The combination of collagen plus probiotics is an excellent two-pronged approach to a more youthful appearance.1

    What is the source of collagen peptides in Mie Collagen + Probiotics?

    The collagen peptides are from a bovine (cow) source. It comes from free-range, grass-fed, hormone-free cows.

    What types of collagen peptides are found in Mie Collagen + Probiotics?

    The collagen peptides are predominantly Types I and III and some Type II. Type I collagen is a major constituent of the bone, tendons, ligaments, and skin. It is the most abundant collagen type found in the skin and throughout the body. Type III collagen is often identified with type I collagen and is found in muscle, blood vessels, and the skin. The amount of Type III collagen found within body is strongly influenced by age. As time progresses, a person makes less of these types of collagens. The collagen made within the body over time is also of poorer quality.1

    Why doesn't Mie Collagen + Probiotics contain other types of collagens like Types V and X?

    There may be some benefits to these types of collagens, but there is little to no human trial research to support their effectiveness. PURE carefully selected ingredients that have strong scientific support of their benefits and efficacy.

    What can you tell me about the other probiotics in Mie Collagen + Probiotics?

    The other probiotics in Mie Collagen + Probiotics include Bifidobacterium lactis, Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium breve, Lactobacillus casei, and Streptococcus thermophilus. These probiotics also support the gut-skin axis. Like most probiotics, these strains can also help boost a healthy digestive tract and immune system. They can help promote a positive mood and may support a healthy cardiovascular system.1

    If I am taking Mie Collagen + Probiotics, do I still need to use my probiotic product?

    It is safe to take Mie and other probiotic products together. You really cannot get too many probiotics. Mie Collagen + Probiotics does contain some of the same probiotic species found in Probiotic. These include Lactobacillus plantarum, Bifidobacterium lactis, Lactobacillus acidophilus, Bifidobacterium longum, and Bifidobacterium breve. These will also provide skin, digestive and immune system support. Keep in mind that PURE Probiotic also contains prebiotics, which are not found in Mie. Prebiotics are like food for probiotics and help to support the proliferation of healthy bacteria in the digestive tract.1

    What is the potency or how many CFU (colonizing forming units) from the probiotics do I get from Mie Collagen + Probiotics?

    Each serving contains 17 billion CFU at the time of manufacture. Of these, 10 billion CFU come from the Lactobacillus plantarum (HY7714) and 7 billion from Bifidobacterium lactis, Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium breve, Lactobacillus casei, and Streptococcus thermophilus.

    Mie Collagen + Probiotics and PURE Probiotic both contain Lactobacillus plantarum. What makes them different?

    While these are the same genus and species of probiotic, the Lactobacillus plantarum (HY7714) is a different strain. Only the HY7714 strain in Mie Collagen + Probiotics is patented and clinically evaluated to support skin health and appearance. The Lactobacillus plantarum in Probiotic will not offer these same benefits since it is a different strain altogether. When classifying probiotics, you have the genus (in this case Lactobacillus) and the species (in this case plantarum). In some instances, unique strains are created from a specific genus and species of probiotics. HY7714 is a unique strain obtained from Lactobacillus plantarum, so it will not act the same in the body as just Lactobacillus plantarum.1

    How should Mie Collagen + Probiotics be stored?

    Mie Collagen + Probiotics contains the unique and novel probiotic strain called Lactobacillus plantarum (HY7714). This live probiotic is best stored at room temperatures about 74° F out of direct sunlight. If desired, it can also be stored in the refrigerator. Do not freeze.

    Will LivePURE have a vegan version of Mie Collagen + Probiotics available?

    It might surprise you to hear that plant sourced collagen does not actually exist. There are vegan products available, which promote collagen production in the body, but these products do not actually contain collagen protein or peptides. These products could be compared to our Organic Sulfur, which supports collagen production in the body, but does not actually provide a dietary source of collagen. However, working in a laboratory, scientists recently have been able to recreate the amino acid structure of collagen. While not from a plant source, this will pave the way for the development of non-animal sourced, vegan friendly collagen products.

    What is the age recommendation for Mie Collagen + Probiotics?

    Mie Collagen + Probiotics is a very safe and beneficial product when taken as recommended. While not harmful to teenagers, you should consider that younger persons make ample quantities of collagen.

    Can Mie Collagen + Probiotics help treat acne?

    Persistent acne is a medical condition, which should be evaluated by licensed medical professional, preferably a dermatologist.

    How long will it take before I start seeing the benefits of Mie Collagen + Probiotics?

    Some benefits will be felt right away while other benefits may take some time. The favorable effects of the probiotics on the digestive tract, for example, will be more immediate. Skin hydration and reduction in the appearance of fine lines and wrinkles will take longer. We recommend continuous use of this product for at least 4 weeks. Some of the benefits of Mie are gradual, so we recommend using the product continuously.1

    When is the best time to take Mie Collagen + Probiotics?

    We recommend taking this first thing in the morning, but it can be taken anytime of the day. Collagen consists of specific amino acids, which are best absorbed on an empty stomach. For best results, we recommend consuming this product in the morning and not mixed with other protein containing foods or products like one of our Protein Nutrition Shakes.

    How should I take Mie Collagen + Probiotics?

    Mix one stick into eight ounces (1 cup) of cold water and drink immediately to help ensure the maximum benefits of the probiotics.

    Can I take Mie Collagen + Probiotics more than once daily?

    You could take up to 2 servings a day, but one serving of Mie Collagen + Probiotics is really all that is needed to see the incredible benefits from this product.

    What other PURE products pair well with Mie Collagen + Probiotics?

    Organic Sulfur is an excellent companion product to Mie Collagen + Probiotics. The main and only ingredient in Organic Sulfur is methylsulfonylmethane (MSM) and is a rich source of sulfur. Sulfur is a key component of collagen known for its structural importance of healthy skin and joints. In clinical trial, Organic Sulfur's MSM was shown to improve skin firmness, hydration, and minimize the appearance of fine lines and wrinkles. Acai superfruit juice is another great supporting product to Mie. Acai, also known as the beauty berry, contains potent antioxidants that help protect the skin.

    Can supplemental biotin interfere with medical blood test results?

    One serving of Mie contains 5,000 mcg (5 mg) of biotin. Higher amounts of biotin may affect some immunoassay blood test results causing them to be either increased or decreased falsely. These tests include troponin, thyroid hormone tests, cortisol and vitamin D levels. Some case reports falsely indicated hyperthyroidism and Graves disease in individuals taking 10 to 300 mg (10,000 to 300,000 mcg) of biotin per day.

    References

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    2. Altobelli GG, Noorden SV, Balato A, Cimini V. Copper/Zinc superoxide dismutase in human skin: current knowledge. Frontiers in Medicine 2020 10.1016/j.clindermatol.2010.03.037
    3. Angas RT, Gile GE. Goodson MS, Karl JP, et. al. Evaluation of probiotics for warfighter health and performance. Frontiers Nutrition 2020 doi: 10.3389/fnut.2020.00070
    4. Barbesino G. Misdiagnosis of Graves' disease with apparent severe hyperthyroidism in a patient taking biotin megadoses. Thyroid 2016;26:860-3.
    5. Biscolla RPM, Chiamolera MI, Kanashiro I, Maciel RMB, Vieira JGH. A single 10 mg oral dose of biotin interferes with thyroid function tests. Thyroid 2017;27:1099-1100.
    6. Cashman MW, Sloan SB Nutrition and Nail Disease. Clinics in Dermatology 2010, 10.1016/j.clindermatol.2010.03.037
    7. Czajka A, Kania EM, Genovese L, Corbo A, Merone G, Luci C, Sibilla S. Daily oral supplementation with collagen peptides combined with vitamins and other bioactive compounds improves skin elasticity and has a beneficial effect on joint and general well-being. Nutrition Research 2018, 57:97-108. https://doi.org/10.1016/j.nutres.2018.06.001
    8. Elston MS, Sehgal S, Du Toit S, Yarndley T, Conaglen JV. Factitious Graves' disease due to biotin immunoassay interference–a case and review of the literature. J Clin Endocrinol Metab 2016;101:3251-5.
    9. Fallacara A, Baldini E, Manfredini S, Vertuani S. Hyaluronic acid in the third millennium. Polymers 2018; 10, 701; doi:10:3390/polym1070701
    10. Geng R, Kang S-G, Huang K, Tong T. Boosting the photoaged skin: the potential role of dietary components. Nutrients. 13, 1691 https://doi.org/10.3390/nu13051691
    11. Gil MI, Tomas-Barberan FA, Hess-Pierce B, Holcroft DM, Kader AA. Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J Agric. Food Chem. 2000,48:4581-4589.
    12. Kerry RG, Patra JK, Gouda S, Park Y, Shin HS, Das G. Benefaction of probiotics for human health: a review. J Food and Drug Anal 2018;26:927-937.
    13. Kober MM, Bowe WP. The effect of probiotics on immune regulation, acne, and photoaging. Intl J Women's Derm. 2015; 1:85-89.
    14. Kummer S, Hermsen D, Distelmaier F. Biotin treatment mimicking Graves' disease. N Engl J Med 2016;375:704-6.
    15. Lee K, Kim HJ, Kim SA, Park SD, Shim JJ, Lee JL. Exopolysaccharide from Lactobacillus plantarum HY7714 protects against skin aging through skin-gut axis communication. Molecules 2021, 26,1651, https://doi.org/10.3390/molecules26061651
    16. Lee S-Y, Lee E, Park YM, S-J, Hong. Microbiome in the Gut-skin axis in atopic dermatitis. Allergy Asthma Immunol Res. 2018, 10(4):354-362. doi.org/10.4168/aair.2018.10.4.354
    17. Li Y, Guo C, Yang J, Wei J, Xu J, Cheng S. Evaluation of antioxidant properties of pomegranate peel extract in comparison with pomegranate pulp extract. Food Chemistry 2006, 254-260.
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    32. Shigemura Y, Kubomura D, Sato Y, Sato K. Dose-dependent changes in the levels of free and peptide forms of hydroxyproline in human plasma after collagen hydrolysate ingestion Food Chem, 2014, 159:328-332.
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    PRODUCT PHOTO

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