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  • Generic Name: (phentermine hydrochloride)
    Other Brands: N/A
  • Last Revised: 02/2015
    • What is this medication and its most common uses?

      Adipex-P is a medicine used for short-term (a few weeks) treatment for obesity, in addition to diet and exercise.

      Adipex-P is a federally controlled substance because it has abuse potential.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Adipex-P is thought to work by suppressing your appetite.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: When used as an add-on to diet and exercise, Adipex-P may help you lose more weight than dieting alone.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Adipex-P exactly as your healthcare provider has prescribed.

      How do I know it is working?

      You may start to notice a decrease in your weight. This is a good indicator that your medication is working. Your healthcare provider may ask you questions from time to time to assess how well your medicine is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: increased blood pressure, constipation, dizziness, headache, restlessness, rash, changes in your sex drive.

      Less common side effects may include:

      Mental and physical dependence can occur. Keep Adipex-P in a safe place to prevent misuse and abuse.

      Pulmonary hypertension (high blood pressure in the arteries of the lungs), with symptoms such as shortness of breath, unexplained chest pain, fainting, or swelling of your legs and feet.

      Adipex-P may also cause heart problems.

    • Who should not take this medication?

      Do not take Adipex-P if you are allergic to it or any of its ingredients.

      Do not take Adipex-P if you have a history of heart disease (such as a stroke, abnormal heart beat or rhythm, or high blood pressure that is not controlled).

      Do not take Adipex-P if you are very anxious, tense, or agitated.

      Do not take Adipex-P if you have a history of drug abuse.

      Do not take Adipex-P if you have an overactive thyroid gland or glaucoma (high pressure in the eye).

      Do not take Adipex-P if you are pregnant or breastfeeding.

      Do not take Adipex-P if you take another medicine called a monoamine oxidase inhibitor (MAOI) (such as phenelzine, selegiline, or linezolid), a class of medications used to treat depression and other conditions. Do not start taking Adipex-P if you stopped taking an MAOI in the last 2 weeks.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Adipex-P. Also, talk to your healthcare provider about your complete medical history, especially if you have heart problems, high blood pressure, diabetes, seizures, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults >16 years: The usual dose is one capsule or one tablet once a day. Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

    • How should I take this medication?

      Take Adipex-P exactly as prescribed by your healthcare provider. Do not change your dose or take Adipex-P more often without first talking to your healthcare provider.

      Take Adipex-P either 1 hour before breakfast or 2 hours after breakfast. Avoid taking Adipex-P in the late evening because it may cause restlessness and trouble sleeping.

    • What should I avoid while taking this medication?

      Do not drink alcohol or take medications that make you sleepy while taking Adipex-P.

      Do not drive a car, operate heavy machinery, or engage in other dangerous activities until you know how Adipex-P affects you.

      Do not take Adipex-P with other over-the-counter, herbal, or prescription weight loss medications (such as fluoxetine, sertraline, fluvoxamine, or paroxetine). Adipex-P should be taken only as short-term, single therapy treatment for obesity.

    • What are the possible food and drug interactions associated with this medication?

      If Adipex-P is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Adipex-P with the following: alcohol, diabetes medications (such as insulin or metformin), or MAOIs.

    • May I receive this medication if I am pregnant or breastfeeding?

      Adipex-P can harm your unborn baby if taken during pregnancy. Do not take Adipex-P if you are pregnant or breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Adipex-P, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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