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Daraprim is a medicine used in combination with other medicines to treat certain infections, such as toxoplasmosis and malaria. It is also used to prevent malaria.
How does this medication work?
Daraprim is thought to stop the growth of certain organisms causing your infection.
What are the beneficial effects of this medication and when should I begin to have results?
What: By stopping the growth of certain organisms causing the infection, Daraprim may help to relieve your symptoms and eliminate the infection.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Daraprim exactly as your healthcare provider has prescribed.
How do I know it is working?
Your healthcare provider may order certain tests to check how well this medication is working.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: allergic reactions, loss of appetite, vomiting, low blood cell counts.
Less common side effects may include:
Daraprim may increase the risk of developing cancer.
Do not take Daraprim if you are allergic to it or any of its ingredients.
Do not take Daraprim if you have a history of a certain type of anemia (low red blood cell counts) due to folate deficiency.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Daraprim. Also, talk to your healthcare provider about your complete medical history, especially if you have seizures, kidney or liver problems, malabsorption syndrome, if you drink alcohol, or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The usual starting dose is 50 to 75 milligrams (mg) a day.
Children: Your healthcare provider will prescribe the appropriate dose for your child, based on his/her weight.
Your healthcare provider may adjust the dose as needed, until the desired effect is achieved.
Adults: The usual dose is 25 or 50 mg for 2 days.
Children 4-10 years: The usual dose is 25 mg for 2 days.
Adults and children >10 years: The usual dose is 25 mg (1 tablet) once a week.
Children 4-10 years: The usual dose is 12.5 mg (1/2 tablet) once a week.
Children <4 years: The usual dose is 6.25 mg (1/4 tablet) once a week.
Take Daraprim exactly as prescribed by your healthcare provider. Do not change your dose or stop taking it without first talking to your healthcare provider.
If you experience a rash, sore throat, paleness, or a swollen tongue, stop taking Daraprim and notify your healthcare provider immediately.
If you experience loss of appetite or vomiting, you may take Daraprim with meals.
Do not become pregnant or plan to become pregnant without first checking with your healthcare provider.
If Daraprim is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Daraprim with the following: certain sulfonamides (such as sulfamethoxazole), lorazepam, methotrexate, phenytoin, proguanil, or zidovudine.
The effects of Daraprim during pregnancy are unknown. Daraprim can be found in your breast milk if you take it while breastfeeding. Do not breastfeed while you are taking Daraprim. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of Daraprim, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature, in a dry place. Protect from light.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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